Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Length and Framing of Anti-Junk Food Ads Impact Inclinations to Consume Junk Food Among Normal Weight, Overweight, and Adults With Obesity. [PDF]
Hollett RC +4 more
europepmc +1 more source
Purpose To assess the availability, price transparency, and pricing of platelet‐rich plasma (PRP), bone marrow aspirate concentration, and stem cell injections for knee osteoarthritis (OA) among orthopaedic sports medicine (OSM) practices and alternative clinics in suburban New York and to evaluate the impact of the economic status of a population on ...
Tracy M. Tauro +6 more
wiley +1 more source
Supplementary description of <i>Boulenophrys elongata</i> (Anura, Megophryidae): Sexual dimorphism and observations on reproductive behaviours. [PDF]
Wang J +6 more
europepmc +1 more source
Purpose To determine the effect of various postoperative ambulation and bracing protocols on hamstring muscle group activation in healthy volunteers. Methods Hamstring muscle group activation was assessed via Myontec Mbody 3 Shorts. Volunteers ambulated 10 yards in conditions including walking unassisted, flat‐foot weightbearing (FFWB), FFWB with a ...
Christian E. Athanasian +5 more
wiley +1 more source
The Feasibility and Cost-Effectiveness of Tailored Social Media Advertising to Recruit Sexual and Gender Minority Adolescents in the Southern United States: Online Survey Study. [PDF]
Lambert D, Luisi N.
europepmc +1 more source
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo +9 more
wiley +1 more source
Audience Interpretation of Risks in Health Promotion Campaigns About Underage Drinking: Qualitative Interviews With Parents of Adolescents. [PDF]
Nguyen HV.
europepmc +1 more source
Immersive virtual reality as a teaching tool in neuroanatomy: A scoping review
Abstract Basic core courses in various undergraduate programs, such as neuroanatomy, pose a challenge for students due to the large volume and complexity of the content. In this context, educational technologies such as immersive virtual reality (IVR), which allow students to actively interact with learning materials, offer a complementary pedagogical ...
Nathálya Gardênia de Holanda Marinho Nogueira +7 more
wiley +1 more source
Perceptions of Somali American male young adults in Salt Lake City about social media marketing of e-cigarettes: a pilot study. [PDF]
Onigbogi O +4 more
europepmc +1 more source

