Results 121 to 130 of about 3,319,467 (307)
Investment Advice: Go for the MBA [PDF]
, 2007 Business school deans have been rushing to the defense of their graduate degree programs ever since Jeffrey Pfeffer and Christina Fong published their 2002 article questioning the value of an MBA. Not only did those authors debate the worth of the MBA in
Holtom, Brooks, Inderrieden, Edward
core +1 more source
Advanced Science, EarlyView.The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia +15 more
wiley +1 more source
Modelling Phosphorus for Grassland: Agronomically and Environmentally Sustainable Advice [PDF]
, 2006 End of project reportIn 2006, the Nitrates Directive (through S.I. 378 (Anon, 2006)) was implemented in Ireland, aimed at reducing nutrient losses from agriculture to water bodies, i.e. surface waters, groundwater and estuarine waters.
Schulte, Rogier P.
core
Growth‐Like Swelling of 2D Precursors for Efficient Fabrication of Complex 3D Microstructures
Advanced Science, EarlyView.The growth‐like swelling process fills photocured polymers into the elastomeric microstructures, inducing a significant swelling deformation of microstructures that can be maintained in the absence of solvents. The growth‐like swelling process breaks through the dependence of swelling deformation on the solvents, thereby expanding the application of 3D
Xinkai Zhu +13 more
wiley +1 more source
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Challenging assumptions about “moving online” in response to COVID-19, and some practical advice
MedEdPublish, 2020 COVID-19 is forcing many Universities to close for some time and programmes for medical, allied health, and nursing students are moving online. Based on our extensive collective experience teaching a variety of health professionals in clinical and ...
Tim Fawns, Derek Jones, Gillian Aitken
doaj
Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
We develop a model of consulting (advising) where the role of the consultant is that she can reveal signals to her client which refine the client’s original private estimate of the profitability of a project.
Balázs Szentes, Péter Eso
core
Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source