Results 111 to 120 of about 1,057,698 (355)

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Report of the Research Review Mission to the Near East and North Africa [PDF]

open access: yes, 1973
Report on the findings of the research review mission sent to the Middle East and North Africa to evaluate the status of existing research in the region and its capacity in addressing the problems of irrigated and rainfed agriculture. Research priorities
CGIAR Technical Advisory Committee
core  

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

Front Page and Advisory Committee

open access: yesConservation Science in Cultural Heritage, 2008
Salvatore Lorusso
doaj   +1 more source

CGIAR Priorities and Strategies: The Process [PDF]

open access: yes, 1995
This record contains a transmittal letter from the TAC Chairman covering six papers for discussion by the CGIAR at ICW95 as part of the process of revising CGIAR priorities and strategies.
CGIAR Technical Advisory Committee
core  

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras   +19 more
wiley   +1 more source

Conflicts of interest for members of the US 2020 dietary guidelines advisory committee

open access: yesPublic Health Nutrition
Objectives: To measure incidence of conflicts of interest (COI) with food and pharmaceutical industry actors on the advisory committee for the 2020–2025 US Dietary Guidelines for Americans (DGA) and assess the adequacy of current mechanisms to disclose ...
Mélissa Mialon   +5 more
doaj   +1 more source

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