Results 51 to 60 of about 186,801 (313)
Molecular Oncology, EarlyView.Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda +3 more
wiley +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Future Deep Inelastic Scattering with the LHeC [PDF]
arXiv, 2018 For nearly a decade, Guido Altarelli accompanied the Large Hadron electron Collider project, as invited speaker, referee and member of the International Advisory Committee. This text summarises the status and prospects of the development of the LHeC, with admiration for a one-time scientist and singular leader whom I met first nearly 40 years ago under
arxiv
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Report of the Dark Energy Task Force [PDF]
arXiv, 2006 Dark energy appears to be the dominant component of the physical Universe, yet there is no persuasive theoretical explanation for its existence or magnitude. The acceleration of the Universe is, along with dark matter, the observed phenomenon that most directly demonstrates that our theories of fundamental particles and gravity are either incorrect or ...
arxiv
The 2020 Updated Roadmaps for the US Magnet Development Program [PDF]
arXiv, 2020 The US Magnet Development Program brings together teams from the leading US accelerator magnet research programs to develop the next generation of magnet technology for future collider applications. Sponsored by the DOE Office of High Energy Physics, the program strives to maintain and strengthen US Leadership in the field, while nurturing cross ...
arxiv
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Ground-Based Direct Detection of Exoplanets with the Gemini Planet Imager (GPI) [PDF]
arXiv, 2007 The Gemini Planet (GPI) imager is an "extreme" adaptive optics system being designed and built for the Gemini Observatory. GPI combines precise and accurate wavefront control, diffraction suppression, and a speckle-suppressing science camera with integral field and polarimetry capabilities.
arxiv
A Physician Advisory System for Chronic Heart Failure Management Based on Knowledge Patterns [PDF]
, 2016 Management of chronic diseases such as heart failure, diabetes, and chronic obstructive pulmonary disease (COPD) is a major problem in health care. A standard approach that the medical community has devised to manage widely prevalent chronic diseases such as chronic heart failure (CHF) is to have a committee of experts develop guidelines that all ...
arxiv +1 more source
FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source