Results 51 to 60 of about 547 (137)

Comparative analyses of seven algorithms for copy number variant identification from single nucleotide polymorphism arrays [PDF]

, 2010
10.1093/nar/gkq040Nucleic Acids Research389e105 ...
Dellinger, A.E., Goh, L.K., Li, Y.-J., Saw, S.-M., Seielstad, M., Young, T.L.   +5 more
core   +3 more sources

Between-centre differences for COVID-19 ICU mortality from early data in England. [PDF]

, 2020
Since the first cases in November 2019, the spread of SARS-CoV-2 infections has placed unprecedented strain on healthcare. The intensive care unit (ICU) is of particular concern as large numbers of patients with severe respiratory complications mean that

core   +2 more sources

Human antibody VH domains targeting uPAR as candidate therapeutics for cancers [PDF]

, 2023
The high expression of uPAR has been linked to tumor progression, invasion, and metastasis in several types of cancer. Such overexpression of uPAR makes it a potential target for immunotherapies across common cancers such as breast, colorectal, lung ...
Dimiter S. Dimitrov, Dimiter S. Dimitrov, Ilya Lyakhov, John W. Mellors, John W. Mellors, Margaret G. Hines, Wei Li, Xiaojie Chu   +7 more
core   +1 more source

TRAJECTORY CLUSTERING USING LATENT CLASS MODELS FOR UNSUPERVISED TBI BIOMARKER TEMPORAL PHENOTYPE DISCOVER [PDF]

, 2018
Background: TBI biomarkers display population-level time-varying kinetics [1] which may be a rich source of pathobiological information [2]. At an individual level, deviations from stereotypical trajectories may represent different pathological processes
Bellander, Bo-Michael, Dixit, Abhishek, Ercole, Ari, Lindblad, Caroline, Nelson, David W, Risling, Marten, Svensson, Mikael, Thelin, Eric P   +7 more
core   +1 more source

Systematics of two-component superconductivity in $YBa_{2}Cu_{3}O_{6.95}$ from microwave measurements of high quality single crystals

, 1997
Systematic microwave surface impedance measurements of YBCO single crystals grown in $BaZrO_3$ crucibles reveal new properties that are not directly seen in similar measurements of other YBCO samples.
A. A. Golubov, A. Andreone, A. Erb, A. Erb, A. Erb, A. Erb, A. Junod, A. M. Tikofsky, B. E. C. Koltenbah, B. G. Storey, C. J. Stevens, C. O'Donovan, C. Panagopoulos, C. W. Chu, D. A. Bonn, D. C. Mattis, D. J. Harlingen, D. van der Marel, E. Brecht, E. Roddick, E. T. Heyen, E. Walker, H. Casalta, H. Ikuta, H. K. Olsson, H. Srikanth, H. Srikanth, I. Maggio-Aprile, I. Maggio-Aprile, J. Betouras, J. Buan, J. C. Booth, J. F. Annett, J. Ma, J. Mao, J. R. Waldram, J.-Y. Genoud, K. A. Muller, K. Zhang, M. B. Salamon, M. C. Nuss, M. Covington, M. Fogelstrom, M. L. Horbach, M. Roulin, M. Roulin, M. T. Beal-Monod, M. V. Indenbom, N. Klein, N. Overend, P. H. Dickinson, P. J. Hirschfeld, R. A. Klemm, R. B. Laughlin, R. Combescot, R. Gagnon, S-F. Lee, S. Hensen, S. Kamal, S. M. Anlage, S. Sridhar, S. Sridhar, T. Jacobs, T. Jacobs, T. Jacobs, T. R. Lemberger, T. Shibauchi, T. Xiang, V. J. Emery, V. Z. Kresin, W. N. Hardy, Y. Ren, Z. Ma, Z. Zhai, Z.-X. Shen   +74 more
core   +1 more source

Resuscitation of patients with active Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) status after out-of-hospital cardiac arrest. [PDF]

, 2019
Victims of out-of-hospital cardiac arrest (OHCA) will often already be living with serious or life- threatening chronic co-morbidities. Many patients express wishes that they would not want to be resuscitated in the event of a cardiac arrest. Analysis of
Barnard, EBG, Ercole, A, Nicholls, T, Sandbach, DD, Wilson, A   +4 more
core   +1 more source

Thermosensory TRPV Heterotetramers Drive Seasonal Polyphenism: Molecular Basis of CcIav/CcNan‐PKCα‐AKH/AKHR Signaling in Pear Psyllid Morph Transition

Advanced Science, Volume 12, Issue 45, December 4, 2025.
At 2 5 °C, thermal activation initiates: i) CcIav/CcNan heterotetramer assembly → Ca2⁺ influx; ii) CcPKCα phosphorylation → AKH signaling potentiation; iii) CcAKH1 binding to membrane‐localized CcAKHR → energy mobilization (lipid catabolism/glycogenolysis) and vitellogenin transport via follicular patency; iv) Oocyte maturation → summer‐form nymph ...
Jianying Li, Zhixian Zhang, Yilin Wang, Yue Yang, Jiarui Wang, Xueyi Ruan, Songdou Zhang   +6 more
wiley   +1 more source

Stroma Targeting Nuclear Imaging and Radiopharmaceuticals

International Journal of Molecular Imaging, Volume 2012, Issue 1, 2012., 2012
Malignant transformation of tumor accompanies profound changes in the normal neighboring tissue, called tumor stroma. The tumor stroma provides an environment favoring local tumor growth, invasion, and metastatic spreading. Nuclear imaging (PET/SPECT) measures biochemical and physiologic functions in the human body.
Dinesh Shetty, Jae-Min Jeong, Hyunsuk Shim, Izabela Tworowska   +3 more
wiley   +1 more source

Guidelines for Data Acquisition, Quality and Curation for Observational Research Designs (DAQCORD). [PDF]

, 2020
BACKGROUND: High-quality data are critical to the entire scientific enterprise, yet the complexity and effort involved in data curation are vastly under-appreciated.
Brinck, Vibeke, DAQCORD collaborators, Ercole, Ari, George, Pradeep, Hicks, Ramona, Huijben, Jilske, Jarrett, Michael, Vassar, Mary, Wilson, Lindsay   +8 more
core   +2 more sources

Hypoxia‐Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou, Shuying Qiu, Xia Yang, Yan Wu, Xinxia Yao, Hangqi Hu, Jingfeng Luo, Chandra Sugiarto Wijaya, Lingfeng Ma, Xiaojun Long, Lingna Xu, Jinquan Liu, Chaoqun Wang, Yibin Pan, Xiaona Chen, Hongchuan Jin, Xian Wang   +16 more
wiley   +1 more source