Results 61 to 70 of about 547 (137)

Assessment of Total-Body Atherosclerosis by PET/Computed Tomography [PDF]

open access: yes, 2021
Atherosclerotic burden has become the focus of cardiovascular risk assessment. PET/computed tomography (CT) imaging with the tracers 18F-fluorodeoxyglucose and 18F-sodium fluoride shows arterial wall inflammation and microcalcification, respectively ...
Alavi, Abass   +4 more
core   +1 more source

PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma

open access: yesClinical and Translational Medicine, Volume 15, Issue 3, March 2025.
Citrullinization is a post‐translational modification that has rarely been studied. Our research found that enzyme peptididylarginine deiminase 4 (PADI4) facilitates the citrullination of protein arginine methyltransferase 2 (PRMT2), a process essential for the stabilization of PRMT2 expression and the enhancement of its function in promoting the ...
Zeyu Wang   +14 more
wiley   +1 more source

Evaluation of the relationship between slow-waves of intracranial pressure, mean arterial pressure and brain tissue oxygen in TBI: a CENTER-TBI exploratory analysis [PDF]

open access: yes, 2021
Export Date: 16 February 2023; Cited By: 7Peer ...
Cabeleira, Manuel   +6 more
core   +1 more source

An analysis of human causal factors in Unmanned Aerial Vehicle (UAV) accidents [PDF]

open access: yes, 2014
MBA Professional ReportHuman error has been identified as the major contributor in many severe aviation mishaps, even for accidents involving Unmanned Aircraft (UA) systems.
Oncu, Mehmet, Yildiz, Suleyman
core   +1 more source

Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice

open access: yesAdvanced Science, Volume 11, Issue 39, October 23, 2024.
The diagram depicts the protective mechanism of HMF on renal fibrosis. Briefly, NEU4 is highly expressed in fibrotic kidneys. Mechanistically, NEU4254‐388aa interacts with Yap at WW2 domain (231‐263aa), preventing its phosphorylation, promoting its nucleus translocation and activation of target genes (CTGF et al), thereby promoting renal fibrosis.
Ping‐Ting Xiao   +9 more
wiley   +1 more source

Pulmonary embolism following complex trauma: UK MTC observational study. [PDF]

open access: yes, 2019
OBJECTIVES: To describe the incidence of pulmonary embolism (PE) in a critically ill UK major trauma centre (MTC) patient cohort. METHODS: A retrospective, multidataset descriptive study of all trauma patients requiring admission to level 2 or 3 care in ...
Carrothers, Andrew D   +7 more
core   +1 more source

BUB1/KIF14 complex promotes anaplastic thyroid carcinoma progression by inducing chromosome instability

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 7, April 2024.
Abstract Chromosome instability (CIN) is a common contributor driving the formation and progression of anaplastic thyroid cancer (ATC), but its mechanism remains unclear. The BUB1 mitotic checkpoint serine/threonine kinase (BUB1) is responsible for the alignment of mitotic chromosomes, which has not been thoroughly studied in ATC.
Tiefeng Jin   +13 more
wiley   +1 more source

Identifying Biomarkers in Lymph Node Metastases of Esophageal Adenocarcinoma for Tumor-Targeted Imaging [PDF]

open access: yes, 2020
INTRODUCTION: Tumor-targeted imaging is a promising technique for the detection of lymph node metastases (LNM) and primary tumors. It remains unclear which biomarker is the most suitable target to distinguish malignant from healthy tissue in esophageal ...
Baart, V. M.   +10 more
core   +2 more sources

Evaluation of the self-inflating bag-valve-mask and non-rebreather mask as preoxygenation devices in volunteers. [PDF]

open access: yes, 2012
OBJECTIVE: To evaluate and compare the effectiveness and tolerability of preoxygenation with the self-inflating bag-valve-mask (BVM) and non-rebreather mask (NRM) as are used before emergency anaesthesia. DESIGN: Device performance evaluation.
Ercole, Ari, Robinson, Amelia
core   +1 more source

In Silico Model of Critical Cerebral Oxygenation after Traumatic Brain Injury: Implications for Rescuing Hypoxic Tissue. [PDF]

open access: yes, 2019
Cerebral oxygen delivery is central to the modern intensive care of patients with severe traumatic brain injury. Low brain tissue oxygen tension (PbtO2) results from microvascular collapse and diffusion limitation and is associated with adverse outcome ...
Ercole, Ari   +2 more
core   +1 more source

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