Results 1 to 10 of about 207 (134)

A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity. [PDF]

PLoS ONE, 2022
Non-invasive biomarkers of non-alcoholic fatty liver disease (NAFLD) supporting diagnosis and monitoring disease progression are urgently needed. The present study aimed to establish a bioinformatics pipeline capable of defining and validating NAFLD ...
Christoffer A Hagemann, Christian Legart, Mathias B Møllerhøj, Martin R Madsen, Henrik H Hansen, Merete J Kønig, Frederik Helgstrand, Flemming P Hjørne, Anders Toxværd, Jill L Langhoff, Urd L Kielgast, Lise L Gluud, Helene Ægidius, Kristoffer T G Rigbolt, Tina Vilsbøll, Jacob Jelsing, Filip K Knop   +16 more
doaj   +3 more sources

Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease [PDF]

Disease Models & Mechanisms, 2021
The current understanding of molecular mechanisms driving diabetic kidney disease (DKD) is limited, partly due to the complex structure of the kidney.
Frederikke E. Sembach, Helene M. Ægidius, Lisbeth N. Fink, Thomas Secher, Annemarie Aarup, Jacob Jelsing, Niels Vrang, Bo Feldt-Rasmussen, Kristoffer T. G. Rigbolt, Jens C. Nielsen, Mette V. Østergaard   +10 more
doaj   +2 more sources

Sex-Differences in Oral Anticoagulant-Related Intracerebral Hemorrhage [PDF]

Frontiers in Neurology, 2022
Introduction and AimData remain limited on sex-differences in patients with oral anticoagulant (OAC)-related intracerebral hemorrhage (ICH). We aim to explore similarities and differences in risk factors, acute presentation, treatments, and outcome in ...
Josefine Grundtvig, Josefine Grundtvig, Christian Ovesen, Thorsten Steiner, Thorsten Steiner, Thorsten Steiner, Cheryl Carcel, David Gaist, Louisa Christensen, Louisa Christensen, Jacob Marstrand, Jacob Marstrand, Per Meden, Per Meden, Sverre Rosenbaum, Helle K. Iversen, Helle K. Iversen, Christina Kruuse, Christina Kruuse, Thomas Christensen, Karen Ægidius, Inger Havsteen, Hanne Christensen, Hanne Christensen   +23 more
doaj   +2 more sources

Underlying causes of cryptogenic stroke and TIA in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study – the importance of comprehensive clinical evaluation [PDF]

BMC Neurology, 2023
Background Cryptogenic stroke is a heterogeneous condition, with a wide spectrum of possible underlying causes for which the optimal secondary prevention may differ substantially. Attempting a correct etiological diagnosis to reduce the stroke recurrence
B. Ratajczak-Tretel, A. Tancin Lambert, R. Al-Ani, K. Arntzen, G. K. Bakkejord, H. M.O. Bekkeseth, V. Bjerkeli, G. Eldøen, A. K. Gulsvik, B. Halvorsen, G. A. Høie, H. Ihle-Hansen, S. Ingebrigtsen, C. Kremer, S. B. Krogseth, C. Kruuse, M. Kurz, I. Nakstad, V. Novotny, H. Naess, R. Qazi, M. K. Rezaj, D. M. Rørholt, L. H. Steffensen, J. Sømark, H. Tobro, T. C. Truelsen, L. Wassvik, K. L. Ægidius, D. Atar, A. H. Aamodt   +30 more
doaj   +2 more sources

Multidimensional landscape of non-alcoholic fatty liver disease-related disease spectrum uncovered by big omics data: Profiling evidence and new perspectives. [PDF]

Smart Med, 2023
Development of omics technologies, such as RNA‐seq, metabonomics, lipidomics, ST RNA‐seq, ATAC‐seq, microbiome‐seq, SC RNA‐seq and others, promotes voluminous profiling data in NASH‐related disease into clinical medicine. Abstract Characterized by hepatic lipid accumulation, non‐alcoholic fatty liver disease (NAFLD) is a multifactorial metabolic ...
Zhu Z, Chen Y, Qin X, Liu S, Wang J, Ren H.   +5 more
europepmc   +2 more sources

Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis [PDF]

BMC Gastroenterology, 2020
Background Animal models of non-alcoholic steatohepatitis (NASH) are important tools in preclinical research and drug discovery. Gubra-Amylin NASH (GAN) diet-induced obese (DIO) mice represent a model of fibrosing NASH.
Henrik H. Hansen, Helene M. Ægidius, Denise Oró, Simon S. Evers, Sara Heebøll, Peter Lykke Eriksen, Karen Louise Thomsen, Anja Bengtsson, Sanne S. Veidal, Michel Feigh, Malte P. Suppli, Filip K. Knop, Henning Grønbæk, Diego Miranda, James L. Trevaskis, Niels Vrang, Jacob Jelsing, Kristoffer T. G. Rigbolt   +17 more
doaj   +2 more sources

Significance of arterial spin labeling perfusion and susceptibility weighted imaging changes in patients with transient ischemic attack: a prospective cohort study [PDF]

BMC Medical Imaging, 2018
Background In a prospective cohort of patients with transient ischemic attack (TIA), we investigated usefulness and feasibility of arterial spin labeling (ASL) perfusion and susceptibility weighted imaging (SWI) alone and in combination with standard ...
Inger Havsteen, Lasse Willer, Christian Ovesen, Janus Damm Nybing, Karen Ægidius, Jacob Marstrand, Per Meden, Sverre Rosenbaum, Marie Norsker Folke, Hanne Christensen, Anders Christensen   +10 more
doaj   +2 more sources

Correction to: Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC) [PDF]

The Journal of Headache and Pain, 2018
Following the publication of this article [1], the authors noticed that they incorrectly reported the Absolute risk of ischemic stroke in women aged 20 to 44 years in relation to the use of hormonal contraception and migraine status due to a ...
Simona Sacco, Gabriele S. Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E. Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Per Morten Sandset, Paolo Martelletti, on behalf of the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC)   +15 more
doaj   +2 more sources

Comparison of 3- and 20-Gradient Direction Diffusion-Weighted Imaging in a Clinical Subacute Cohort of Patients with Transient Ischemic Attack: Application of Standard Vendor Protocols for Lesion Detection and Final Infarct Size Projection [PDF]

Frontiers in Neurology, 2017
ObjectiveDiffusion tensor imaging may aid brain ischemia assessment but is more time consuming than conventional diffusion-weighted imaging (DWI). We compared 3-gradient direction DWI (3DWI) and 20-gradient direction DWI (20DWI) standard vendor protocols
Inger Havsteen, Christian Ovesen, Lasse Willer, Janus Damm Nybing, Karen Ægidius, Jacob Marstrand, Per Meden, Sverre Rosenbaum, Marie Norsker Folke, Hanne Christensen, Anders Christensen   +10 more
doaj   +2 more sources

Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020 [PDF]

The Journal of Headache and Pain, 2021
Headache and facial pain are among the most common, disabling and costly diseases in Europe, which demands for high quality health care on all levels within the health system.
Henrik W. Schytz, Faisal M. Amin, Rigmor H. Jensen, Louise Carlsen, Stine Maarbjerg, Nunu Lund, Karen Aegidius, Lise L. Thomsen, Flemming W. Bach, Dagmar Beier, Hanne Johansen, Jakob M. Hansen, Helge Kasch, Signe B. Munksgaard, Lars Poulsen, Per Schmidt Sørensen, Peter T. Schmidt-Hansen, Vlasta V. Cvetkovic, Messoud Ashina, Lars Bendtsen   +19 more
doaj   +2 more sources