Results 1 to 10 of about 9,242 (187)

Apoptotic signatures allow early and rapid screening of drug-induced liver injury to accelerate drug discovery [PDF]

Communications Medicine
Background Early detection of drug-induced liver injury (DILI) during drug development is crucial for reducing drug attrition and ensuring the safety of patients. A versatile, biologically interpretable, and dose-dependent screening approach is therefore
John Hellgren, Bhavik Chouhan, Aydar Uatay, Ramy Elgendy, Julia Lindgren, Naoko Toki, Alessandro Bonetti, Aditi Chaudhari, Kenneth Pryde, Patrik Andersson, Marie Kalm, Fredrik Karlsson, Johanna Sagemark, Dominic P. Williams, Jennifer Y. Tan, Bino John, John Gallon   +16 more
doaj   +2 more sources

Comparative analysis of esophageal gland microbes between two body sizes of Gigantopelta aegis, a hydrothermal snail from the Southwest Indian Ridge [PDF]

Microbiology Spectrum
Microbial communities within animals provide nutritional foundation and energy supply for the hydrothermal ecosystem. The peltospirid snail Gigantopelta aegis forms large aggregation in the Longqi vent field on the Southwest Indian Ridge.
Anning Mou, Xinlong Li, Zhong Li, Lingyun Qu, Yue Dong, Zongling Wang, Xuelei Zhang, Qinzeng Xu   +7 more
doaj   +2 more sources

AEGIS: Individual-based modeling of life history evolution. [PDF]

PLoS Computational Biology
Nature presents a staggering diversity of life history strategies, ranging from rapid to slow onset of sexual maturity, short or long life, low or high number of offspring, and much more.
Martin Bagic, Arian Šajina, William John Bradshaw, Dario Riccardo Valenzano   +3 more
doaj   +2 more sources

Multidimensional Linear Cryptanalysis of AEGIS

IACR Transactions on Symmetric Cryptology
AEGIS is a family of authenticated encryption with associated data (AEAD) ciphers that target for highly efficient implementations in software. The main operation in AEGIS is the AES encryption round function such that it can make full use of the ...
Yinuo Liu, Tian Tian, Jing Yang
doaj   +2 more sources

Randomized prospective trial to detect and distinguish between medication nonadherence, drug-drug interactions, and disease progression in chronic cardiometabolic disease

BMC Primary Care, 2023
Background Disentangling nonadherence (NA), drug-drug interactions (DDIs), and disease progression from each other is an important clinical challenge for providers caring for patients with cardiometabolic diseases.
John W Peabody, Divya Ganesan, Czarlota Valdenor, David Paculdo, Joshua Schrecker, Christopher Westerfield, Rebecca Heltsley   +6 more
doaj   +1 more source

AEGIS: Agent oriented organisations [PDF]

Accounting, Management and Information Technologies, 1995
Abstract Today's enterprises are faced with highly dynamic, sometimes even hostile environments. This paper discovers that the two most prominent organizational strategies addressing these challenges, namely that of widespread decentralization and of business process orientation, are inherently conflicting.
Unland, R. (Rainer), Kirn, S. (Stefan), Wanka, U. (Ulrich), O'Hare, G.M. (Gregory), Abbas, S.   +4 more
openaire   +6 more sources

Anti-missile defense directional characteristics modeling of Aegis warship formation [PDF]

Zhihui kongzhi yu fangzhen, 2023
Through flexible configuration of warship formation, the Aegis Warship Formation achieves interception and defense of targets in different attack directions.
LIU Yong, SONG Yanqi, ZHOU Hongchao, LIANG Wei
doaj   +1 more source

MILP‐based security evaluation for AEGIS/Tiaoxin‐346/Rocca

IET Information Security, 2023
In this paper, the security of Advanced Encryption Standard‐based authenticated encryption schemes, including AEGIS family, Tiaoxin‐346, and Rocca by mixed integer linear programming tools is examined. Specifically, for the initialisation phase of AEGIS,
Takuro Shiraya, Nobuyuki Takeuchi, Kosei Sakamoto, Takanori Isobe   +3 more
doaj   +1 more source

Synthesis of a measuring composite signal for assessing the security of speech signals during discrete-quantized transformation

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2020
The purpose of the work is to systematically analyze and generalize a high-precision measuring signal for assessing the security in leakage channels in high-level noise by discrete-quantized representation of speech signals using the principles of ...
V. K. Zheleznjak, S. V. Lavrov, A. G. Filipovich, M. M. Baranouski   +3 more
doaj   +1 more source

A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase

Nature Communications, 2023
Artificially Expanded Genetic Information Systems (AEGIS) add independently replicable unnatural nucleotide pairs to the natural G:C and A:T/U pairs found in native DNA, joining the unnatural pairs through alternative modes of hydrogen bonding.
Juntaek Oh, Zelin Shan, Shuichi Hoshika, Jun Xu, Jenny Chong, Steven A. Benner, Dmitry Lyumkis, Dong Wang   +7 more
doaj   +1 more source