Results 51 to 60 of about 413,172 (344)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Tinker, Mapper, Soldier, Spy – Captain Henry Elsdale’s Pioneering 1882–83 Experiment with Small Balloons and Vertical Aerial Photography in Halifax, Canada

Canadian Journal of Remote Sensing, 2019
The first aerial photography trials in Canada took place at Halifax, Nova Scotia, in 1882 and 1883. They are attributed to an Englishman, Captain Henry Elsdale (1842–1900) of the Royal Engineers Corps.
Dirk Werle
doaj   +1 more source

Cost-Effectiveness of Seven Approaches to Map Vegetation Communities — A Case Study from Northern Australia’s Tropical Savannas

Remote Sensing, 2013
Vegetation communities are traditionally mapped from aerial photography interpretation. Other semi-automated methods include pixel- and object-based image analysis.
Stuart Phinn, Lara Arroyo, Donna Lewis
doaj   +1 more source

UAV 3D Modeling and Application Based on Railroad Bridge Inspection

Buildings, 2023
Unmanned aerial vehicle (UAV) remote sensing technology is vigorously driving the development of digital cities. For experimental objects such as large, protruding, and structurally complex steel truss railway bridge structures, commonly used oblique ...
Zhiyuan Tang, Yipu Peng, Jian Li, Zichao Li   +3 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Aerial Video Trackers Review

Entropy, 2020
Target tracking technology that is based on aerial videos is widely used in many fields; however, this technology has challenges, such as image jitter, target blur, high data dimensionality, and large changes in the target scale.
Jinlu Jia, Zhenyi Lai, Yurong Qian, Ziqiang Yao   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source

Pemetaan Cepat Kawasan Terdampak Bencana Longsor dan Banjir di Kabupaten Bangli, Provinsi Bali

Majalah Geografi Indonesia, 2017
Abstrak Teknologi penginderaan jauh mengalami perkembangan yang sangat pesat. Salah satunya adalah teknologi akuisisi data dengan menggunakan UAV (Unmanned Aerial Vehicle).
Theresia Retno Wulan, Wiwin Ambarwulan, Anggara S. Putra, Mega D Putra, Dwi Maryanto, Ferrari Pinem, Edwin Maulana   +6 more
doaj   +1 more source