Results 101 to 110 of about 288,912 (350)

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Spotted Seals, Phoca largha, in Alaska [PDF]

open access: yes, 1997
The worldwide literature on management of spotted seals, Phoca largha, was reviewed and updated, and aerial surveys weref lown in 1992 and 1993 to determine the species' distribution and abundance in U.S. waters.
Rugh, David J.   +2 more
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A review of California sea otter, Enhydra lutris, surveys [PDF]

open access: yes, 1986
Recent surveys (1977 to 1983) of the sea otter, Enhydra lutris, in California were summarized and compared to past surveys, to evaluate the adequacy of current survey design and to-make inferences about current population status.
Ames, Jack A.   +2 more
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

UAVs in Context: Archaeological Airborne Recording in a National Body of Survey and Record

open access: yesDrones, 2017
Historic Environment Scotland (HES) is the lead public body which investigates, promotes and cares for the historic environment in Scotland. It undertakes a range of archaeological airborne work from detailed documentation of individual sites to ...
David C. Cowley   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

An Aerial Gamma Ray Survey of Springfields and the Ribble Estuary in September 1992 [PDF]

open access: yes, 1992
<p>A short aerial gamma ray survey was conducted in the vicinity of the Springfields site and Ribble Estuary from 1st-5th September 1992, to define existing background radiation levels, against which any future changes can be assessed.
Allyson, J.D.   +4 more
core  

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