Results 101 to 110 of about 361,735 (303)
Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Salāmat-i kār-i Īrān, 2011 Background and aims In order to physiologically fit the job to the worker’s capability, maximum aerobic capacity (VO2-max) is used. This study was conducted to estimate VO2-max and determine its associated factors among workers of industrial sector of ...
A. Rajaei Fard +2 more
doaj
Exploring Physiology and Body Traits of Finswimming Athletes and Trained Swimmers
Jurnal Pendidikan Jasmani dan OlahragaIn practical situations, athletes often face certain limitations in the transition to finswimming. Consequently, coaching procedures focus on the conversion of trained-swimmers into finswimming athletes. This study aimed to conduct a comparative analysis
Dadan Resmana +2 more
doaj +1 more source
The Effects and Differences of Sprint Interval Training, Endurance Training and the Training Types Combined on Physiological Parameters and Exercise Performance [PDF]
, 2014 Sprint Interval Training (SIT) is a time efficient way in order to elicit similar changes as Endurance Training (ET) on aerobic capacity, with the purpose of the exercise training to alter physiological systems and exceed resting homeostasis to improve ...
Hurst, Rachel Ann
core +1 more source
Advanced Science, EarlyView.This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang +13 more
wiley +1 more source
Association among 2-min step test, functional level and diagnosis of dementia
Dementia & Neuropsychologia. Aerobic capacity declines significantly throughout life, beginning at the age of 30 years and accelerating from 60 years, where a decline of 17% per decade is expected thereafter.
Jessica Plácido +6 more
doaj +1 more source
Advanced Science, EarlyView.The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Salāmat-i kār-i Īrān, 2016 Background and aims: The maximum aerobic capacity or VO2max is a measure of the maximum volume of oxygen that can be absorbed by respiratory system and delivered to the acting muscles through blood flow.
payam Heydari +3 more
doaj
Effects of Kettlebell Training on Aerobic Capacity
Journal of Strength and Conditioning Research, 2015 This study examined the effects of a kettlebell training program on aerobic capacity. Seventeen female National Collegiate Athletic Association Division I collegiate soccer players (age: 19.7 ± 1.0 years, height: 166.1 ± 6.4 cm, weight: 64.2 ± 8.2 kg) completed a graded exercise test to determine maximal oxygen consumption (V̇O2max).
J Asher, Falatic +5 more
openaire +3 more sources
Advanced Science, EarlyView.Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu +11 more
wiley +1 more source