Results 111 to 120 of about 361,735 (303)
Frontiers in NutritionAerobic exercise capacity is a critical determinant of endurance performance and overall health. Natural medicinal plant polysaccharides (NMPPs) have emerged as promising bioagents to enhance aerobic capacity through multi-target mechanisms.
Mingxin Xu +6 more
doaj +1 more source
Nutrient balance of a two-phase solid manure biogas plant [PDF]
, 2005 So called "dry fermentation" prototype plants for anaerobic digestion of organic material containing 15-50 % total solids show added advantages compared to slurry digestion plants (Hoffman 2001): Less reactor volume, less process energy, less transport ...
Evers, Lars +5 more
core
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Advanced Science, EarlyView.This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao +10 more
wiley +1 more source
Manipulating the ensilage of wilted, unchopped grass through the use of additive treatments [PDF]
, 2007 peer-reviewedBaled silage composition frequently differs from that of comparable conventional precision-chop silage. The lower final concentration of fermentation products in baled silage makes it more conducive to the activities of undesirable ...
Clipson, Nicholas J.W. +4 more
core
Advanced Science, EarlyView.A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang +9 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen +10 more
wiley +1 more source
Predicted Aerobic Capacity of Asthmatic Children: A Research Study from Clinical Origin
Pulmonary Medicine, 2012 Objective. To compare longitudinally PAC of asthmatic children against that of healthy controls during ten months. Methods. Twenty-eight asthmatic children aged 7–15 years and 27 matched controls each performed six submaximal exercise tests on treadmill,
Lene Lochte
doaj +1 more source
The effects of dehydration on the aerobic and anaerobic capacities of men, part IV FINAL scientific report [PDF]
Dehydration effects on work capacity and aerobic capacities of ...
Newton, J. L. +2 more
core +1 more source
Advanced Science, EarlyView.Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans +8 more
wiley +1 more source