Effects of acute exercise on memory: Considerations of exercise intensity, post-exercise recovery period and aerobic endurance. [PDF]
Mem Cognit, 2023 Loprinzi PD +4 more
europepmc +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Effects of 8 weeks of aerobic endurance training on functional capacity and metabolic variables in people with type 1 diabetes: A secondary outcome analysis of the ULTRAFLEXI-1 study. [PDF]
Diabetes Obes Metab, 2023 Müller A +12 more
europepmc +1 more source
Multi-Stage 20-m Shuttle Run Fitness Test, Maximal Oxygen Uptake and Velocity at Maximal Oxygen Uptake. [PDF]
, 2014 The multi-stage 20-m shuttle run fitness test (20mMSFT) is a popular field test which is widely used to measure aerobic fitness by predicting maximum oxygen uptake (VO2max) and performance.
Argeitaki, P +5 more
core +2 more sources
Advanced Science, EarlyView.This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao +10 more
wiley +1 more source
Life-long exercise training and inherited aerobic endurance capacity produce converging gut microbiome signatures in rodents. [PDF]
Physiol Rep, 2022 Anhê FF +9 more
europepmc +1 more source
Training benefits consequent to 8-weeks of kettlebell training [PDF]
, 2012 This study was designed to examine the changes in aerobic capacity and muscular strength consequent to 8 weeks of kettlebell training. Seventeen subjects (9 males, 8 females) completed 1 repetition maximum (1RM) testing for one-arm shoulder press, leg ...
Beltz, Nicholas M.
core +1 more source
Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases
Advanced Science, EarlyView.Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh +17 more
wiley +1 more source
Fiyz̤, 2022 Background: Heat shock protein 60 (HSP60) is considered as an indicator of mitochondrial stress and plays a role in modulating mitochondrial dysfunction.
Mehrzad Shabani +3 more
doaj
Correction to: Aerobic endurance training to improve cognition and enhance recovery in schizophrenia: design and methodology of a multicenter randomized controlled trial. [PDF]
Eur Arch Psychiatry Clin Neurosci, 2021 Maurus I +21 more
europepmc +1 more source