Results 141 to 150 of about 115,025 (337)

SIRT4 Promotes Pancreatic Cancer Stemness by Enhancing Histone Lactylation and Epigenetic Reprogramming Stimulated by Calcium Signaling

open access: yesAdvanced Science, EarlyView.
As a downstream target of α2δ1‐mediated calcium signaling, SIRT4 serves as an oncogene to promote the stemness of pancreatic cancer via deacetylating ENO1 directly at K358, leading to attenuated ENO1's RNA‐binding capacity, enhanced glycolytic substrate 2‐PG binding and robust glycolytic activity to increase the level of lactate that induce histone ...
Mengzhu Lv   +10 more
wiley   +1 more source

Serrated Leaf‐Like N‐Doped Copper Sulfide Enabling Bifunctional Oxygen Reduction/Evolution via Dual‐Mode Cathode Reactions for High Energy Density and Cycle Stability in Zinc–Air Batteries

open access: yesAdvanced Science, EarlyView.
A serrated leaf‐like nitrogen‐doped copper sulfide (N‐CuS) cathode with hybridized N 2p – S 3p orbitals is presented, mesopores for oxygen transport, and a five times larger electrochemical active surface area than Cu. In aerobic conditions, a zinc–air battery with N‐CuS achieves 788 mAh g⁻¹ and 916 Wh kg⁻¹, outperforming Pt/C+RuO₂.
Do Hwan Jung   +8 more
wiley   +1 more source

Aerobic Fitness, Acute Exercise and Sleep in Older Men

open access: bronze, 1993
Jack D. Edinger   +6 more
openalex   +1 more source

Changes in Bone Turnover Induced by Aerobic and Anaerobic Exercise in Young Males [PDF]

open access: bronze, 1998
Henning W. Woitge   +8 more
openalex   +1 more source

Cryo‐EM Analysis of a Tri‐Heme Cytochrome‐Associated RC‐LH1 Complex from the Marine Photoheterotrophic Bacterium Dinoroseobacter Shibae

open access: yesAdvanced Science, EarlyView.
Cryo‐EM reveals a closed 17‐subunit LH ring encircling the RC‐LH1 complex in Dinoroseobacter shibae, featuring a novel helix‐turn‐helix subunit bridging RC and LH. Mg2⁺/Ca2⁺ stabilizes the complex, while periplasmic Cyt c₂ mediates electron transfer via a tri‐heme Cyt to the special pair of bacteriochlorophylls. Insights into energy/electron efficiency
Weiwei Wang   +12 more
wiley   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

open access: yesAdvanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li   +9 more
wiley   +1 more source

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