Results 141 to 150 of about 305,456 (350)
Advanced Science, EarlyView.CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang +8 more
wiley +1 more source
Advanced Science, EarlyView.Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
Advanced Science, EarlyView.Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei +12 more
wiley +1 more source
Integrative Omics Reveal Female‐Specific Benefits of p16+ Cell Clearance in Aging Mice
Advanced Science, EarlyView.Aging causes accumulation of p16⁺ senescent cells that promote inflammation and dysfunction. Multi‐omics analyses reveal striking sex differences in senescent cell burden and clearance: females accumulate more p16⁺ cells, especially in the liver, and their removal rejuvenates molecular and functional profiles.
Yao Lin +4 more
wiley +1 more source
Potential for Aerobic Exercise to Release Growth Factors to Induce Cognitive Changes in Children with Autism Spectrum Disorder [PDF]
, 2016 Autism Spectrum Disorder (ASD) is becoming increasingly prevalent among adolescents, and while the number of individuals diagnosed with the disorder grows, there continues to be no cure or even a clear treatment path for ASD.
Harrington, Maya
core +1 more source
Global Evidence of the Unimodal Response of Ecosystem Respiration to Soil Moisture
Advanced Science, EarlyView.Using global eddy covariance observations and a field experiment, this paper provides compelling evidence for the widespread unimodal relationship between soil moisture and ecosystem respiration and its water adaptation. Such knowledge facilitates understanding of soil moisture in affecting respiratory carbon emissions and has the potential to improve ...
Jinlong Peng +9 more
wiley +1 more source
Effects of Aerobic Exercise Intensity on Serum Leptin Levels in Obese/Overweight Women
مجله دانشکده پزشکی اصفهان, 2012 Background: The purpose of this study was to determine the effect of aerobic exercise intensity on serum leptin levels in obese/overweight women. Methods: A total number of 45 obese/overweight women (body mass index ≥ 25-30 kg/m2) were selected from ...
Neda Ghadiri Bahram Abadi +3 more
doaj
Oxidative Stress Response to Short Duration Bout of Submaximal Aerobic Exercise in Healthy Young Adults [PDF]
, 2011 The purpose of this study was to investigate the oxidative stress response to a short duration bout of submaximal exercise in a cohort of healthy young adults.
Brown, Michael D. +4 more
core +1 more source
The effect of aerobic exercise on the number of migraine days, duration and pain intensity in migraine: a systematic literature review and meta-analysis [PDF]
, 2019 Joris Lemmens +7 more
openalex +1 more source
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source