Results 161 to 170 of about 305,456 (350)

Assessing Energy Level as a Marker of Aerobic Exercise Readiness: A Pilot Investigation [PDF]

open access: yes, 2017
International Journal of Exercise Science 10(1): 62-75, 2017. Energy ratings have been used as a marker of exercise readiness (i.e. pre-exercise physical/mental state indicating ability to perform) within flexible nonlinear periodization (FNLP)-based ...
Strohacker, Kelley   +4 more
core   +2 more sources

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

open access: yesAdvanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang   +9 more
wiley   +1 more source

Questioning the Resistance/Aerobic Training Dichotomy: A commentary on physiological adaptations determined by effort rather than exercise modality [PDF]

open access: yes
This paper discusses and challenges the current opinion that exercise adaptation is generally defined by modality; resistance exercise (RE), or aerobic exercise (AE).
Fisher, James, Steele, James
core  

Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li   +11 more
wiley   +1 more source

A Catalog of “Knee Friendly” Aerobic Exercises Developed for Patients With Knee Osteoarthritis: An International Patient Survey

open access: yesACR Open Rheumatology
Objective Aerobic exercise is recommended for the management of knee osteoarthritis (OA), but knee pain is often a barrier for participation. Some types of aerobic exercise may be less painful to undertake than others, though little is known about which ...
Mathilde Espe Pedersen   +10 more
doaj   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

open access: yesAdvanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian   +11 more
wiley   +1 more source

Environmental and Ecological Monitoring with Biodegradable Technologies

open access: yesAdvanced Science, EarlyView.
This review examines the development and application of wireless biodegradable sensors for environmental monitoring. It explores (bio)degradable materials, their degradation mechanisms in various environments, and non‐toxic fabrication techniques. Additionally, it addresses scalable production and sustainable powering solutions, emphasizing the high ...
Mohammad Javad Bathaei   +7 more
wiley   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

open access: yesAdvanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang   +6 more
wiley   +1 more source

Hyperpathia and Aerobic Exercise [PDF]

open access: yesInternational Journal of Sports and Exercise Medicine, 2020
Jiménez-Sáez J. C.   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy