Results 41 to 50 of about 305,456 (350)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Contamination by an Active Control Condition in a Randomized Exercise Trial. [PDF]
PLoS ONE, 2016 Contamination is commonly overlooked in randomized trials. The present study examined contamination (minutes of aerobic activity outside of exercise sessions) within an active control condition in a 6-month randomized exercise trial for older adults.
Diane K Ehlers +4 more
doaj +1 more source
PENGARUH LATIHAN AEROBIK DAN ANAEROBIK TERHADAP AMBANG ANAEROBIK [PDF]
, 2004 This research is aimed at demonstrating: 1) the effects of aerobic exercise towards the increase of anaerobic threshold, 2) the effects of anaerobic exercise towards the anaerobic threshold, 3) the difference in effectiveness of aerobic and anaerobic ...
Suharjana, Suryanto
core
FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source
The Effects of Yoga and Aerobic Exercise on Concentration and Feeling-States [PDF]
, 2011 The impacts of yoga and aerobic exercise on level of concentration and change in feeling-states were examined in this study. They hypothesis was that concentration and feeling-states would improve over a yoga and aerobic exercise session, but yoga, a ...
Dolde, Elyse J.
core +1 more source
Beneficial effects of exercise: shifting the focus from body weight to other markers of health [PDF]
, 2009 Background: Exercise is widely promoted as a method of weight management, while the other health benefits are often ignored. The purpose of this study was to examine whether exercise-induced improvements in health are influenced by changes in body weight.
Blundell, John +4 more
core +2 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Aerobic exercise, an effective prevention and treatment for mild cognitive impairment
Frontiers in Aging Neuroscience, 2023 Aerobic exercise has emerged as a promising intervention for mild cognitive impairment (MCI), a precursor to dementia. The therapeutic benefits of aerobic exercise are multifaceted, encompassing both clinical and molecular domains.
Baiqing Huang, Kang Chen, Ying Li
doaj +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Exercise for lower limb osteoarthritis : systematic review incorporating trial sequential analysis and network meta-analysis [PDF]
, 2013 Objective: To determine whether there is sufficient evidence to conclude that exercise interventions are more effective than no exercise control and to compare the effectiveness of different exercise interventions in relieving pain and improving function
Dziedzic, Krysia S. +6 more
core +4 more sources