Results 41 to 50 of about 3,547,135 (240)

The Effect of Aerobic Training Combined with Garlic Supplementation on Total Antioxidant Capacity and Protein Carbonyl in the Brain Tissue of Aged Rats with Parkinson’s Disease [PDF]

مجله علوم پزشکی صدرا
Introduction: Parkinson’s disease is the second most common neurodegenerative disease after Alzheimer’s disease. Therefore, the present research aims to evaluate the effect of eight weeks of aerobic training combined with garlic supplementation on brain ...
Morteza Hossienzadeh, Asieh Abbassi-Daloii, Seyed Alii Hosieni, Ahmad Abdi   +3 more
doaj   +1 more source

The Impact of Aerobic and Resistance Training on C-Reactive Protein (CRP) and Lipid Profiles in Methadone-Treated Addicted Men [PDF]

Journal of Basic Research in Medical Sciences, 2023
Introduction: The combined use of methadone and exercise training holds promise for promoting health. This study investigates the impact of resistance and aerobic training in conjunction with methadone consumption on lipid profiles and C-reactive protein
Rasoul Chegol, Mandana Gholami, Hasan Matinhomaee, Hossein Abed Natanzi, Farshad Ghazalian   +4 more
doaj  

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Influence of aerobic exercise training on post-exercise responses of aortic pulse pressure and augmentation pressure in postmenopausal women

Frontiers in Physiology, 2015
Central arterial blood pressure (BP) is more predictive of future cardiovascular events than is brachial BP because it reflects the BP load imposed on the left ventricle with greater accuracy.
Nobuhiko eAkazawa, Song-Gyu eRa, Song-Gyu eRa, Jun eSugawara, Seiji eMaeda   +4 more
doaj   +1 more source

A combined continuous and interval aerobic training improves metabolic syndrome risk factors in men. [PDF]

, 2015
Individuals with metabolic syndrome have significantly higher risk for cardiovascular disease, Type 2 diabetes leading to premature death mortality. Metabolic syndrome has a complex aetiology, thus it may require a combined and multi-targeted aerobic ...
Sari-Sarraf V, Esmaeili H, Naderali MM, Sari-Sarraf, Vahid, Naderali EK, Naderali, Mohammad-Mahdi, Aliasgarzadeh, Akbar, Naderali, Ebrahim, Aliasgarzadeh A   +8 more
core   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Aerobic Energy Expenditure and Intensity Prediction During a Specific Circuit Weight Training: a Pilot Study [PDF]

, 2010
During circuit weight training (CWT), workloads, index of intensity as well as estimation of energy expenditure (EE) have been under estimated. The aim of this study was to describe and evaluate physiological variables and gender related differences ...
Álvarez Sánchez, María, Ana Belén Peinado Lozano, Benito Peinado, Pedro José, Peinado Lozano, Ana Belen, Díaz Molina, Víctor, Francisco Javier Calderón Montero, Víctor Díaz Molina, Pedro José Benito Peinado, María Álvarez Sánchez, Calderón Montero, Francisco Javier   +9 more
core   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source