Results 131 to 140 of about 10,509 (314)

Aerodynamics Analysis of Helicopter Rotor in Flight Test Using Strain Gauge Sensors

open access: yesSensors
The acquisition of aerodynamic loads on helicopter rotors is fundamental to the study of helicopter performance optimization, structural design, flight control, and other aspects.
Shuaike Jiao, Jiahong Zheng
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Relative assessment of different turbulence models in prediction of airfoil characteristics for a wide range of angle of attack [PDF]

open access: yes
Simulation of separated flow past an airfoil beyond stall, along with the prediction of stall itself still remains a challenging problem. In practical design and analysis problems of aerodynamics involving turbulent flow, the most widely used ...
Majumdar, Sekhar   +2 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Modelling and simulation of flexible aircraft : handling qualities with active load control [PDF]

open access: yes, 2011
The study of the motion of manoeuvring aircraft has traditionally considered the aircraft to be rigid. This simplifying assumption has been shown to give quite accurate results for the flight dynamics of many aircraft types.
Andrews, Stuart P.
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Calculation of aerodynamic forces

open access: yesCONFERENCE MATERIALS, 2020
openaire   +1 more source

Navier-Stokes Prediction of the Effect of the Skids on the Aerodynamics of Helicopter Fuselage in Forward Flight

open access: yes, 2006
A series of three-dimensional Navier-Stokes computations were carried out with and without skids to investigate the influence of the skids on the flow field and aerodynamic forces acting on a helicopter fuselage in low Mach number forward flight under ...
Khier, Walid
core  

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