Results 61 to 70 of about 5,414,929 (281)

THE AERODYNAMIC ANALYSIS OF THE PROFILES FOR FLYING WINGS [PDF]

Journal of Defense Resources Management, 2013
The possibility of using an un-piloted aerial vector is determined by the aerodynamic characteristics and performances. The design for a tailless unmanned aerial vehicles starts from defining the aerial vector mission and implies o series of geometrical ...
Vasile PRISACARIU
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Analysis of aerodynamic characteristics of hypersonic folding-wing aircraft

Hangkong gongcheng jinzhan
Hypersonic aircraft encounter challenges in adapting to complex external environments during missions. Conventional fixed-wing aircraft have limited optimal aerodynamic performance under specific conditions.
WU Zaoping, QIN Jian, WU Jie
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Aerodynamic characteristics of a rotating sphere

IOP Conference Series: Materials Science and Engineering, 2020
Abstract Modern ballistic models, both internal and external, are amazingly accurate. This is due in no small part to the advances in technology that reduced tolerances in the guns and provided testing equipment that provided consistent and valid results. There are few variables.
K R Crawford, N W Mitiukov, E L Busygina
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Layout and Rotation Effect on Aerodynamic Performance of Multi-Rotor Ducted Propellers

Drones
Multi-rotor ducted propellers, which integrate the high-efficiency characteristics of ducted propellers with the layout flexibility and safety advantages of distributed propulsion, are extensively utilized in the propulsion systems of low-altitude ...
Zeyu Li, Jianghao Wu, Pengyu Zhang, Lin Wang, Long Chen, Zhengping Zou, Haiying Lin   +6 more
doaj   +1 more source

PrandtlPlane High–Lift System Preliminary Aerodynamic Design [PDF]

, 2006
An analysis of low-speed aerodynamics for an unconventional aircraft configuration has been carried out. This configuration, named Prandtlplane, implements Prandtl's Best Wing System for low induced drag.
Iezzi, Giuseppe
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source