Results 101 to 110 of about 20,749 (266)

Comparison of anatomic and aerodynamic characteristics of the upper airway among edentulous mild, moderate, and severe obstructive sleep apnea in older adults. [PDF]

J Clin Sleep Med, 2022
Chen H, Elham E, Li Y, Ge S, Schmittbuhl M, Lavigne G, van der Stelt PF, Huynh N.   +7 more
europepmc   +1 more source

Aerodynamic Characteristics of HYFLEX.

Journal of the Japan Society for Aeronautical and Space Sciences, 1997
WATANABE, Shigeya, ISHIMOTO, Shinji, TAKAKI, Ryoji   +2 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Aerodynamic Analysis of Hovering Flapping Wing Using Multi-Plane Method and Quasi-Steady Blade Element Theory

Applied Sciences
In the design of flapping-wing micro-size air vehicles capable of hovering, wings serve as the primary source of hovering power, making the analysis of aerodynamics and aerodynamic efficiency crucial.
Ruiqi Ye, Ziming Liu, Jin Cui, Chenyang Wang, Yirong Wu   +4 more
doaj   +1 more source

Aerodynamic characteristics in upper airways among orthodontic patients and its association with adenoid nasopharyngeal ratios in lateral cephalograms. [PDF]

BMC Med Imaging, 2021
Feng X, Chen Y, Cai W, Lie SA, Hellén-Halme K, Shi XQ.   +5 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Numerical Simulation Research on Aerodynamic Characteristics during Take-Off Phase in Ski Jumping

Applied Sciences
In view of the inability to directly and accurately obtain an athlete’s aerodynamic force during the take-off phase through the wind tunnel test, the athlete’s aerodynamic force and surrounding flow field form under different take-off postures are ...
Qi Hu, Weidi Tang, Yu Liu
doaj   +1 more source

Numerical study on the influence of wall temperature gradient on aerodynamic characteristics of low aspect ratio flying wing configuration. [PDF]

Sci Rep, 2021
Lin P, Liu X, Xiong N, Wang X, Shang M, Liu G, Tao Y.   +6 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source