Results 111 to 120 of about 5,414,929 (281)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The Refined Simulation Methods of Fluctuating Wind and Aerodynamic Forces Relative to Moving Trains

Applied Sciences
This study proposes a framework to accurately simulate the fluctuating wind and aerodynamic forces relative to moving trains. It provides a novel method for calculating the power spectra of the fluctuating wind relative to moving trains and the time ...
Naijie Yan, Ning Chen, Aiqiong Tang, Yonghua Su, Hui Guo, Qiqi Xiang   +5 more
doaj   +1 more source

The Normative Study of Acoustic and Aerodynamic Characteristics of Voice among Healthy Adult Turkish Speaker Population. [PDF]

Biomed Res Int, 2021
Şen AZ, Toğram B.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Aerodynamic Characteristics of HYFLEX.

Journal of the Japan Society for Aeronautical and Space Sciences, 1997
WATANABE, Shigeya, ISHIMOTO, Shinji, TAKAKI, Ryoji   +2 more
openaire   +2 more sources

Aerodynamic Characteristics and Lateral Displacements of a Set of Two Buildings in a Linked Tall Building System. [PDF]

Sensors (Basel), 2021
Chen Z, Kim B, Lee DE.
europepmc   +1 more source

Transonic aerodynamic loads modeling of X-31 aircraft

, 2012
The generation of reduced order models for computing the unsteady and nonlinear aerodynamic loads on the X-31 aircraft from pitching motions in the transonic speed range is described.
Cummings, R. M., Post, M. L., Da Ronch, A., Badcock, K. J., Ghoreyshi, M.   +4 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Aerodynamic Analysis of Hovering Flapping Wing Using Multi-Plane Method and Quasi-Steady Blade Element Theory

Applied Sciences
In the design of flapping-wing micro-size air vehicles capable of hovering, wings serve as the primary source of hovering power, making the analysis of aerodynamics and aerodynamic efficiency crucial.
Ruiqi Ye, Ziming Liu, Jin Cui, Chenyang Wang, Yirong Wu   +4 more
doaj   +1 more source

Comparison of anatomic and aerodynamic characteristics of the upper airway among edentulous mild, moderate, and severe obstructive sleep apnea in older adults. [PDF]

J Clin Sleep Med, 2022
Chen H, Elham E, Li Y, Ge S, Schmittbuhl M, Lavigne G, van der Stelt PF, Huynh N.   +7 more
europepmc   +1 more source