Results 71 to 80 of about 5,414,929 (281)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Aerodynamic Characteristics of Road Vehicles Overtaking on Bridge Deck under Crosswinds
Advances in Civil Engineering, 2020 The aerodynamic characteristics of road vehicles in windy environments are the prerequisites for the evaluation and prediction of the driving safety and stability.
Ning Chen +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
AerospaceA parafoil is a crucial aerodynamic deceleration device used in the field of airdrop. The overall objective of this paper is to study the aerodynamic characteristics of the curving process of the canopy using the lattice Boltzmann method, to verify it ...
Yi Wang, Chunxin Yang
doaj +1 more source
The influence of aerodynamic coefficients on the elements of classic projectile paths
Vojnotehnički Glasnik, 2011 The article deals with the results of the research on the influence of aerodynamic coefficient values on the trajectory elements and the stability parameters of classic axisymmetric projectiles.
Damir D. Jerković, Dušan B. Regodić
doaj +1 more source
Aerodynamic Shape Optimization Using the Discrete Adjoint of the Navier-Stokes Equations: Applications Toward Complex 3D Configutations [PDF]
, 2009 Within the next few years, numerical shape optimization based on high fidelity methods is likely to play a strategic role in future aircraft design. In this context, suitable tools have to be developed for solving aerodynamic shape optimization problems,
Dwight, Richard P. +5 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Aerodynamic design optimization using flow feature parameterization
, 2007 Design optimization methods using high-fidelity computational fluid dynamics simulations are becoming increasingly popular in the area of aerodynamic design, sustaining the desire to make these methods more computationally efficient.
Barrett, Thomas Robin
core +1 more source
Dipole Approximation in the Calculation of the Perturbed Velocities
Transport and Telecommunication, 2014 In this article we consider one of the approaches aimed at reducing time of calculation of aerodynamic characteristics of the studied objects using discrete vortex method.
Solovyov Oleg +3 more
doaj +1 more source
Low Reynolds Number Propeller Slipstream Interference with Wing Aerodynamic Characteristics
Hangkong gongcheng jinzhan, 2018 Detailed research for wing aerodynamic characteristics of propeller slipstream at low Reynolds number could contribute the mechanism study of low speed near space flow, and provide reliable aerodynamic results.
Sun Kaijun, Bao Xiaoxiang, Fu Yiwei
doaj +1 more source