Results 111 to 120 of about 5,415,034 (233)

MULTI-OBJECTIVE OPTIMIZATION DESIGN OF MW WIND TURBINE AIRFOILS

open access: yesJixie qiangdu, 2020
With the development of wind power generation technology,the requirements for various performances of wind turbines are higher. Aerodynamic noise problem has become a key research direction of the wind power industry.
LI YingJue, WEI KeXiang, ZHOU Zhou
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The Refined Simulation Methods of Fluctuating Wind and Aerodynamic Forces Relative to Moving Trains

open access: yesApplied Sciences
This study proposes a framework to accurately simulate the fluctuating wind and aerodynamic forces relative to moving trains. It provides a novel method for calculating the power spectra of the fluctuating wind relative to moving trains and the time ...
Naijie Yan   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Transonic aerodynamic loads modeling of X-31 aircraft

open access: yes, 2012
The generation of reduced order models for computing the unsteady and nonlinear aerodynamic loads on the X-31 aircraft from pitching motions in the transonic speed range is described.
Cummings, R. M.   +4 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Aerodynamic Analysis of Hovering Flapping Wing Using Multi-Plane Method and Quasi-Steady Blade Element Theory

open access: yesApplied Sciences
In the design of flapping-wing micro-size air vehicles capable of hovering, wings serve as the primary source of hovering power, making the analysis of aerodynamics and aerodynamic efficiency crucial.
Ruiqi Ye   +4 more
doaj   +1 more source

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