Results 121 to 130 of about 5,818,028 (293)

MULTI-OBJECTIVE OPTIMIZATION DESIGN OF MW WIND TURBINE AIRFOILS

open access: yesJixie qiangdu, 2020
With the development of wind power generation technology,the requirements for various performances of wind turbines are higher. Aerodynamic noise problem has become a key research direction of the wind power industry.
LI YingJue, WEI KeXiang, ZHOU Zhou
doaj  

Transonic aerodynamic characteristics of two hypersonic cruise configurations [PDF]

open access: yes, 1969
Transonic aerodynamic characteristics of two hypersonic cruise ...
Langhans, R. A.
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Aerodynamic Characteristics of HYFLEX.

open access: yesJournal of the Japan Society for Aeronautical and Space Sciences, 1997
WATANABE, Shigeya   +2 more
openaire   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The Refined Simulation Methods of Fluctuating Wind and Aerodynamic Forces Relative to Moving Trains

open access: yesApplied Sciences
This study proposes a framework to accurately simulate the fluctuating wind and aerodynamic forces relative to moving trains. It provides a novel method for calculating the power spectra of the fluctuating wind relative to moving trains and the time ...
Naijie Yan   +5 more
doaj   +1 more source

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