Results 61 to 70 of about 19,794 (265)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
AerospaceA parafoil is a crucial aerodynamic deceleration device used in the field of airdrop. The overall objective of this paper is to study the aerodynamic characteristics of the curving process of the canopy using the lattice Boltzmann method, to verify it ...
Yi Wang, Chunxin Yang
doaj +1 more source
Simulation on Powered Effects of BWB at Take-off Condition
Xibei Gongye Daxue Xuebao, 2020 The influence of engine powered effects on aerodynamic characteristics of BWB300, which was designed by the Airplane Concept Design Institute of Northwestern Polytechnical University, at take-off condition was analyzed by using the numerical simulation ...
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Aerodynamic characteristics of a rotating sphere
IOP Conference Series: Materials Science and Engineering, 2020 Abstract Modern ballistic models, both internal and external, are amazingly accurate. This is due in no small part to the advances in technology that reduced tolerances in the guns and provided testing equipment that provided consistent and valid results. There are few variables.
K R Crawford, N W Mitiukov, E L Busygina
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Low Reynolds Number Propeller Slipstream Interference with Wing Aerodynamic Characteristics
Hangkong gongcheng jinzhan, 2018 Detailed research for wing aerodynamic characteristics of propeller slipstream at low Reynolds number could contribute the mechanism study of low speed near space flow, and provide reliable aerodynamic results.
Sun Kaijun, Bao Xiaoxiang, Fu Yiwei
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
DEFINITION OF AERODYNAMIC CHARACTERISTICS OF THE PROFILE UNDER THE DRAG POLAR OF THE FINITE WING
Научный вестник МГТУ ГА, 2016 The numerical method of calculation of aerodynamic characteristics of a profile is stated on the basis of the experiment of aerodynamic characteristics of a rectangular wing of a final lengthening.
B. L. Artamonov
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