Results 41 to 50 of about 19,794 (265)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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Механика машин, механизмов и материалов, 2011 The paper presents an overview of research in the field of aerodynamics of bluff bodies and some useful flows which are used in theoretical studies on the aerodynamics of aircraft.
V.S. Karabtsev , D.H. Valeev
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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A Novel Aerodynamic Modeling Method Based on Data for Tiltrotor evtol
Applied SciencesA data-driven aerodynamic modeling method is proposed to address the problem that traditional modeling methods based on physical mechanisms cannot fully represent the special aerodynamic characteristics of tiltrotor evtol aircraft.
Haiyang Wang, Peng Li, Dongsu Wu
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Some solvable non-linear equations related to aerodynamic instability phenomena
Vietnam Journal of Mechanics, 1994 This article proposes some forms of aerodynamic forces, looks for accurate solutions of core - pendent non-linear differential equations and analyses the characteristics of aerodynamic forces and of equation's solution.
Nguyen Dang Bich, Nguyen Vo Thong
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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THE AERODYNAMIC ANALYSIS OF THE PROFILES FOR FLYING WINGS [PDF]
Journal of Defense Resources Management, 2013 The possibility of using an un-piloted aerial vector is determined by the aerodynamic characteristics and performances. The design for a tailless unmanned aerial vehicles starts from defining the aerial vector mission and implies o series of geometrical ...
Vasile PRISACARIU
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