Results 131 to 140 of about 15,596,670 (337)

A review of aerodynamic and wake characteristics of floating offshore wind turbines

open access: yesRenewable & Sustainable Energy Reviews, 2023
Xin-Bao Wang   +7 more
semanticscholar   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Aerodynamic characteristics of wheelchairs [PDF]

open access: yes, 1979
The overall aerodynamic drag characteristics of a conventional wheelchair were defined and the individual drag contributions of its components were determined.
Coe, P. L., Jr.
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Transonic aerodynamic loads modeling of X-31 aircraft pitching motions

open access: yes, 2013
The generation of reduced-order models for computing the unsteady and nonlinear aerodynamic loads on an aircraft from pitching motions in the transonic speed range is described.
Cummings, R.M.   +3 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Aerodynamic noise from a train pantograph

open access: yes, 2014
Many studies have shown that when the speed of high speed trains exceeds around 300km/h, aerodynamic noise becomes the most significant noise source. The pantograph, or current collector, is mounted on the top of the train and is therefore not shielded ...
Liu, Xiaowan   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Aerodynamic characteristics and genesis of aggregates at Sakurajima Volcano, Japan. [PDF]

open access: yesSci Rep, 2022
Vecino MCD   +9 more
europepmc   +1 more source

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