Results 111 to 120 of about 88,513 (307)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Space shuttle: Static aerodynamic and control investigation of an expendable second stage with payload alone and with delta wing booster (B-15B-1) [PDF]

Aerodynamic force and moment coefficients for scale model of expendable second stage modified S-2 alone and mounted piggyback on space shuttle booster from Mach 0.6 to 4 ...
Allen, E. C., Eder, F. W.
core   +1 more source

Sail optimization for upwind sailing: application in a Tornado, the Olympic class catamaran.

, 2008
A study of a boat’s motion is carried out in order to analyze the aerodynamic properties of the optimal sail for obtaining the maximum velocity when sailing to windward.
Ana Laverón-Simavilla, Angel Sanz, CA Marchaj, CJ Wood, JA Sparenberg, NJ Locke, PS Jackson, RGJ Flay, RGJ Flay, Sebastián Franchini, T Sugimoto, Victoria Lapuerta   +11 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Flight-Measured Aerodynamic Loads on a 0.92 Aspect Ratio Lifting Surface [PDF]

Ventral fin loads, expressed as normal force coefficients, bending moment coefficients, and torque coefficients, were measured during flight tests of a YF-12A airplane.
Deangelis, V. M., Meyer, R. R., Jr.
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

The predicted effect of aerodynamic detuning on coupled bending-torsion unstalled supersonic flutter [PDF]

A mathematical model is developed to predict the enhanced coupled bending-torsion unstalled supersonic flutter stability due to alternate circumferential spacing aerodynamic detuning of a turbomachine rotor.
Fleeter, S., Hoyniak, D.
core   +1 more source

CFD simulation of flow past MAV wings [PDF]

, 2011
Turbulent flow past low aspect ratio (AR) thin wing used for two different MAV (Micro Air Vehicles) configurations viz. Black Kite and Golden Hawk has been carried out in order to analyze their aerodynamic characteristics.
Kulkarni, DS, Pradeep, Shetty, Rajani, BN, Subrahmanya, MB   +3 more
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source