Results 121 to 130 of about 15,080 (315)

Data-driven aerodynamic shape optimization of rotor airfoils based on deep learning

open access: yesAdvances in Aerodynamics
As the fundamental component of rotor blades, the airfoil dominates the aerodynamic performance of helicopter rotors. The aerodynamic shape optimization of rotor airfoils is thus an effective means of improving their aerodynamic performance.
Jiaqi Liu   +3 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Optimal Passive Aerodynamic Control Design for Mitigating Flutter in Long-Span Bridges

open access: yesJournal of Applied Science and Engineering
A wide range of studies have focused on improving the aerodynamic stability of long-span bridges by raising their critical flutter wind speed. There are two main approaches to enhancing aerodynamic stability: mechanical and aerodynamic methods.
Hong-Son Nguyen   +4 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Open-Wheel Aerodynamics: Effects of Tyre Deformation and Internal Flow [PDF]

open access: yes, 2013
Competitive performance of an F1 race car relies upon a well designed and highly developed aerodynamic system. In order to achieve this, total understanding of the downstream wake of exposed rotating wheels is essential.
SPROT, ADAM,JOSEPH
core  

Some considerations regarding the use of multi-fidelity Kriging in the construction of surrogate models

open access: yes, 2015
Surrogate models or metamodels are commonly used to exploit expensive computational simulations within a design optimization framework. The application of multi-fidelity surrogate modeling approaches has recently been gaining ground due to the potential ...
Toal, David J.J.
core   +1 more source

Integrated Surrogate Model-Based Approach for Aerodynamic Design Optimization of Three-Stage Axial Compressor in Gas Turbine Applications

open access: yesEnergies
The refined aerodynamic design optimization of multistage compressors is a typical high-dimensional and expensive optimization problem. This study proposes an integrated surrogate model-assisted evolutionary algorithm combined with a Directly Manipulated
Jinxin Cheng   +6 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma   +16 more
wiley   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

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