Results 41 to 50 of about 149,179 (315)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Data-driven aerodynamic shape optimization of rotor airfoils based on deep learning

Advances in Aerodynamics
As the fundamental component of rotor blades, the airfoil dominates the aerodynamic performance of helicopter rotors. The aerodynamic shape optimization of rotor airfoils is thus an effective means of improving their aerodynamic performance.
Jiaqi Liu, Rongqian Chen, Jinhua Lou, Yancheng You   +3 more
doaj   +1 more source

A Coupled Effect Model of Two-Position Local Geometric Deviations on Subsonic Blade Aerodynamic Performance

Applied Sciences, 2020
The coupled aerodynamic performance influence of multiple deviations in the blade profile is a complex phenomena. In this paper, a high-pressure compressor rotor blade mid-span profile is studied with the design of experiments (DOE), numerical simulation
Xianjun Yu, Mingzhi Li, Guangfeng An, Baojie Liu   +3 more
doaj   +1 more source

Influences of main design parameters on the aerodynamic performance of a micro-radial inflow turbine

AIP Advances, 2022
The micro-radial inflow turbine (MRIT) is not only an important component of a micro-gas turbine but also the core part of a vehicle exhaust gas turbocharger and a small-scale organic Rankine circulatory system.
Chao Li, Zhiping Guo, Hao Guo, Xin Bao, Le Zhou   +4 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Aerodynamic Layout Evaluation of Hydrogen-powered Fixed-wing Unmanned Aerial Vehicle(UAV) by Numerical Simulation

Taiyuan Ligong Daxue xuebao, 2021
For the aerodynamic layout selection of a long-endurance hydrogen energy hybrid unmanned aerial vehicle(UAV), this paper carried out a numerical simulation of aerodynamic characteristics for a certain design plan, in order to provide data support for the
Haiping TIAN, Jian SU, Zeqi XIAO, Han WANG, Zhiqiang LI, Jinhui LEI   +5 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

A Review of Intelligent Airfoil Aerodynamic Optimization Methods Based on Data-Driven Advanced Models

Mathematics
With the rapid development of artificial intelligence technology, data-driven advanced models have provided new ideas and means for airfoil aerodynamic optimization.
Liyue Wang, Haochen Zhang, Cong Wang, Jun Tao, Xinyue Lan, Gang Sun, Jinzhang Feng   +6 more
doaj   +1 more source

Increasing L/D Ratio of Wing by Delaying Flow Separation for Better Aerodynamic Performance [PDF]

Journal of Applied Fluid Mechanics
To improve the aerodynamic efficiency of the aircraft, the article focuses on optimizing the L/D ratio through postponement of flow separation. Elevating the L/D ratio leads to diminished drag and delays stall occurrence at high angles of attack (α). The
L. P. Ramesh, V. Mugendiran, G. Sivaraj
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source