Results 121 to 130 of about 121,945 (278)

Investigation of Asymmetric Flow of a Slender Body with Low-Aspect Ratio Fins Having Large Deflection Angles

Aerospace
To understand the asymmetric flow of a slender body with low-aspect ratio fins, a wind tunnel experiment was carried out, and the asymmetric flow was observed when the pair of fins had a symmetric deflection angle of 30° at a small angle of attack and ...
Yonghong Li, Lin Zhang, Chuan Gao, Jilong Zhu, Bin Dong   +4 more
doaj   +1 more source

Application of multidisciplinary optimization methods to the design of a supersonic transport [PDF]

An optimization design method is discussed. This method is based on integrating existing disciplinary analysis and sensitivity analysis techniques by means of generalized sensitivity equations.
Barthelemy, J.-F. M., Coen, P. G., Dovi, Augustine R., Hall, L. E., Riley, M. F., Wrenn, Gregory A.   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Effect of afterbody geometry and sting diameter on the aerodynamic characteristics of slender bodies at mach numbers from 1.57 to 2.86 [PDF]

Afterbody geometry and sting diameter effect on aerodynamics of slender bodies at supersonic ...
Fuller, D. E., Langhans, V. E.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The present status and the future of missile aerodynamics [PDF]

Some recent developments in the state of the art in missile aerodynamics are reviewed. Among the subjects covered are: (1) tri-service/NASA data base, (2) wing-body interference, (3) nonlinear controls, (4) hypersonic transition, (5) vortex interference,
Nielsen, Jack N.
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Adaptive Free-Form Deformation Parameterization Based on Spring Analogy Method for Aerodynamic Shape Optimization

Fluids
An adaptive Free-Form Deformation parameterization method based on a spring analogy is presented for aerodynamic shape optimization problems. The proposed method effectively incorporates the gradients of the objective and constraint functions, achieving ...
Jinxin Zhou, Xiaojun Wu, Hongyin Jia, Jing Yu   +3 more
doaj   +1 more source

Numerical Investigation of the Aerodynamic Properties of a Flying Wing Configuration [PDF]

, 2012
The numerical investigations of a generic UCAV configuration are presented. These investigations are part of the DLR internal project UCAV-2010. Compressible speed conditions are considered and presented.
Huber, Kerstin Claudie, Rein, Martin, Schütte, Andreas   +2 more
core  

Sinusoidal-gust generation with a pitching and plunging airfoil

, 2019
The generation of uniform, periodic gust disturbances in an experimental context is demonstrated using a single oscillating airfoil. A pitching and heaving symmetric airfoil is suggested as a simpler alternative to existing gust-generation methods.
Kissing, Johannes, Tropea, Cameron, Wei, Nathaniel J.   +2 more
core   +1 more source