Results 151 to 160 of about 131,365 (295)

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

open access: yesFEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura   +7 more
wiley   +1 more source

The influence of unsteady aerodynamics on hingeless rotor ground resonance [PDF]

open access: yes
Calculations of the model frequency and damping for a hingeless rotor on a gimballed support in hover are compared with measured results for two configurations (differing in blade flap stiffness). Good correlation is obtaned when an inflow dynamics model
Johnson, W.
core   +1 more source

Analytical and scale model research aimed at improved hangglider design [PDF]

open access: yes, 1979
Research consisted of a theoretical analysis which attempts to predict aerodynamic characteristics using lifting surface theory and finite-element structural analysis as well as an experimental investigation using 1/5 scale elastically similar models in ...
Chang, L. S., Kroo, I.
core   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

Aerodynamics of thrust vectoring [PDF]

open access: yes
Thrust vectoring as a means to enhance maneuverability and aerodynamic performane of a tactical aircraft is discussed. This concept usually involves the installation of a multifunction nozzle.
Lan, C. Edward, Tseng, J. B.
core   +1 more source

A New Actuator Surface Model with Improved Wake Model for CFD Simulations of Rotorcraft [PDF]

open access: yes, 2017
Simulations of rotorcraft operating in unsteady flow-fields, manoeuvring flight, or with complex rotor configurations pose a significant challenge to current simulation methods.
Barakos, Geogre   +3 more
core  

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

open access: yesFEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco   +5 more
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy