Results 171 to 180 of about 21,740 (297)

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

CFD-based aerodynamic optimization of the fairing for a high-speed elevator. [PDF]

Sci Rep
Shen X, Wang A, Liu W, Wang R.
europepmc   +1 more source

Recent trend of rotary wing aerodynamics.

, 1987
Shigeru Saito
openalex   +2 more sources

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

A novel aerodynamic drag-reduction mechanism using dolphin-inspired ultrasonic microvibrations. [PDF]

Sci Rep
Wang D, Liu H.
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Bioinspired Morphing in Aerodynamics and Hydrodynamics: Engineering Innovations for Aerospace and Renewable Energy. [PDF]

Biomimetics (Basel)
Shahid F, Alam M, Park JY, Choi Y, Park CJ, Park HK, Yi CY.   +6 more
europepmc   +1 more source

Effects of Combustor Aerodynamics on the Ignition of Solid Fuel

, 1994
Jing‐Tang Yang, Cliff Yuh-Yih Wu, Hung-Tsann Yang   +2 more
openalex   +1 more source

Periodic Unsteady Flow Aerodynamics and Heat Transfer: Studies on a Curved Surface, Combined Part I and II [PDF]

, 2000
Meinhard T. Schobeiri, Lesley M. Wright, P. Chakka   +2 more
openalex   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source