Results 131 to 140 of about 18,582,204 (254)

Twenty years of inhaler therapy: A nationwide drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to map nationwide trends and prescribing patterns in inhaler use from 2004 to 2023. In light of evolving clinical guidelines and attention to the environmental impact of inhalers within recent years, we also examined variation in prescribing behaviour and patient‐level treatment choices. Methods Using nationwide health registries,
Katrine Bitsch Johansen, Lars Christian Lund, Zandra Nymand Ennis, Andrew Scourfield, Anders Løkke, Sidsel Arnspang Pedersen   +5 more
wiley   +1 more source

Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich, Franziska Friedrich, Daniel Soriano, Jona Gjeloshi, Björn C. Frye, Xuan Phuoc Nguyen, Lydia Herbstritt, Caroline von Spee‐Mayer, Britta Lang, Fabrice Nollevaux, Andreas Hoheisel, Dorothee Winterberg, Armin Braun, Thomas Epting, Christine Contini, Karl Winkler, Thomas Reinheckel, Franziska C. Trudzinski, Gernot Rohde, Daiana Stolz, Robert Bals, Martin J. Hug, Sebastian Wirtz, Christoph Peters, Carolin Jenkner   +24 more
wiley   +1 more source

Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri, Morgan R. Hurst, Kelvin Idanwekhai, Yuxuan Wu, Katherine Ernst, Wai‐Keen Chung, Christopher Bombeck, Saad A. Khan, Sushmita Koley, Gabriella Kiss, Oliver Rammo, Alexander Tropsha, Cristiana Boi, Michael A. Daniele, Steven Cramer, Barry Byrne, Stephen Kaminsky, Angie Snell Bennett, Stefano Menegatti   +20 more
wiley   +1 more source

A thermal evaporator for aerosol core-shell nanoparticle synthesis

Segregated bimetallic nanoparticles like core-shell nanoparticles are of interest in various fields including biomedicine, catalysis, and optoelectronics. Aerosol technology is an optimal platform to control nanoparticle size, structure, and composition,
Namsoon Eom, Knut Deppert, Deppert, Knut, Eom, Namsoon, Maria E. Messing, Markus Snellman, Snellman, Markus, Messing, Maria E., Messing, Maria E.,, Eom, Namsoon,, Deppert, Knut,, Snellman, Markus,, Lund University.   +12 more
core   +1 more source

Molybdenum‐carbothioamide complexes as potential single‐source precursors for MoS2 thin film

Bulletin of the Korean Chemical Society, EarlyView.
Novel molybdenum complexes were synthesized to apply for deposition of Mo‐containing thin films. All complexes were characterized, and they are likely to be used as single‐source precursors for MoS2 thin films. Abstract Molybdenum disulfide (MoS2) thin films are widely used in batteries, transistors, supercapacitors, and 2D materials owing to their ...
Sung Kwang Lee, Dagyum Yoo, Tae Wook Kim, Taek‐Mo Chung   +3 more
wiley   +1 more source

Analisis Proksi Co Terhadap Kondisi Aerosol Di Indonesia

, 2013
Aerosol merupakan salah satu komponen dalam atmosfer yang memiliki peranan besar terhadap proses terjadinya iklim dan cuaca. Namun, pengaruh aerosol terhadap komponen atmosfer lainnya belum diketahui secara akurat dan masih memerlukan berbagai penelitian
Indah Susanti, Nani Cholianawati, Rosida
core  

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Transpirated wall aerosol collection system and method

, 1999
A transpirated wall aerosol collection system includes a collector operable to receive a gas flow containing particulate matter. The system also includes a porous wall having a first surface and a second surface.
McFarland, Andrew R.
core   +1 more source

Profil Aerosol Dan Ozon Di Atas Bandung

, 2001
ABSTRAK Pengamatan aerosol dengan lidar, dan profit ozon dengan .menggunakan ozonsonde telah dilakukan secara bersamaan pada tanggal 26 Maret 1998 di Bandung.
Timbul Manik, Sri Kaloka Ps, Nurlaini, Saipul Hamdi   +3 more
core  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source