Results 191 to 200 of about 4,712,758 (317)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Studying feelings in action: An analytical framework for empirical analyses of affect in sustainability transitions.

Environ Innov Soc Transit
Höhle J, Van Poeck K.
europepmc   +1 more source

Drinking motives and alcohol's acute effects in a social laboratory setting. [PDF]

Psychol Addict Behav
Echeverri CC, Creswell KG, Wright AGC.
europepmc   +1 more source

The generation of student engagement as a cognition-affect-behaviour process in a Twitter learning experience

, 2020
Raúl Pérez‐López, Raquel Gurrea-Sarasa, Carolina Herrando, María José Martín‐De Hoyos, Victoria Bordonaba‐Juste, Ana Utrillas-Acerete   +5 more
openalex   +2 more sources

Thermodynamic Properties of Aqueous Species Calculated Using the HKF Model: How Do Different Thermodynamic and Electrostatic Models for Solvent Water Affect Calculated Aqueous Properties? [PDF]

, 2019
George Dan Miron, Allan M. M. Leal, Alina Yapparova   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Perceived parental relationship quality and adolescent conscious bias: important links between affect, agency, gender, and race/ethnicity. [PDF]

Front Psychol
Terrell A, Merten MJ, Wickrama T.
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A Pilot Observational Study in Ohio, USA of the Healing of Our Veterans Equine Services Intensive Intervention for Veterans with Trauma Histories. [PDF]

Healthcare (Basel)
Held A, Hubbard K, Nazarenko E, Marchand W.   +3 more
europepmc   +1 more source

Affective technology, affective management, towards affective society

Affective technology, affective management, towards affective society
In this paper, the term affective is defined as “being capable to evoke affects in people’s mind” or “being capable to deliberate affects to be evoked in people’s mind”. This paper discusses potential impact of concept of affectiveness on development of technological products and services, management, and value systems of societies. identifier:oai:t2r2.
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