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SIFT: predicting amino acid changes that affect protein function
Nucleic Acids Res., 2003 Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid substitutions in protein-coding regions. Each substitution has the potential to affect protein function. SIFT (Sorting Intolerant From Tolerant) is a program
P. Ng, S. Henikoff
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Neural Plasticity, 2021 Automatic emotion regulation (AER) plays a vital role in the neuropathology underlying both suicide and self-harm via modifying emotional impact effortlessly. However, both the effortless account and the neural mechanisms of AER are undetermined.
Shengdong Chen +6 more
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Frontiers in Psychology, 2022 ObjectivesHostile attribution bias is reportedly common from non-clinical population to those with serious mental illness, such as schizophrenia, and is known to be closely related to theory of mind (ToM).
Se Jun Koo +13 more
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Affective representation and affective attitudes [PDF]
Synthese, 2019 AbstractMany philosophers have understood the representational dimension of affective states along the model of perceptual experiences. This paper argues affective experiences involve a kind of personal level affective representation disanalogous from the representational character of perceptual experiences.
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Stress and Brain, 2021 Anhedonia, as one of the core symptoms of depression, is of great significance for the diagnosis and treatment of depression. Traditionally, anhedonia has been referred to as "loss of pleasure", while the recent research emphasizes that anhedonia is a ...
Jixuan Mao, Jiajin Yuan
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Frontiers in Human Neuroscience, 2018 The present study investigated how pubertal development and sex interact to influence humans’ emotion susceptibility during adolescence. Event-related potentials were recorded for highly emotional, mildly emotional and neutral stimuli in positive and ...
Jiemin Yang +6 more
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Effects of Congenital Blindness on Ultrasonic Vocalizations and Social Behaviors in the ZRDBA Mouse
Frontiers in Behavioral Neuroscience, 2022 Mice produce ultrasonic vocalizations (USVs) at different ages and social contexts, including maternal-pup separation, social play in juveniles, social interactions, and mating in adults.
Nouhaila Bouguiyoud +8 more
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The Benefits of Frequent Positive Affect: Does Happiness Lead to Success?
Psychological bulletin, 2005 Numerous studies show that happy individuals are successful across multiple life domains, including marriage, friendship, income, work performance, and health.
S. Lyubomirsky, L. King, E. Diener
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Frontiers in Behavioral Neuroscience, 2020 Implementation intention has proven effective in regulating intense emotions but is found to be difficult when instructed regulation is used. Here, we aim to test whether automatic reappraisal-based implementation intention (RII) downregulates intense ...
Shengdong Chen +4 more
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Clinical Effectiveness and Efficacy of Chiropractic Spinal Manipulation for Spine Pain
Frontiers in Pain Research, 2021 Spine pain is a highly prevalent condition affecting over 11% of the world's population. It is the single leading cause of activity limitation and ranks fourth in years lost to disability globally, representing a significant personal, social, and ...
Carlos Gevers-Montoro +9 more
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