Results 61 to 70 of about 11,943,637 (389)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
: This article analyses the tension between the perception and performance of affect in two contemporary texts: Heather Christle’s The Crying Book (2019) and Christine Smallwood’s The Life of the Mind (2021).
Raili Marling
doaj +1 more source
Affective Digital Twins for Digital Human: Bridging the Gap in Human-Machine Affective Interaction [PDF]
In recent years, metaverse and digital humans have become important research and industry areas of focus. However, existing digital humans still lack realistic affective traits, making emotional interaction with humans difficult. Grounded in the developments of artificial intelligence, human-computer interaction, virtual reality, and affective ...
arxiv
Putting the affect into affective polarisation
While many believe that affective polarisation poses a significant threat to democratic stability, the definition and operationalisation of the concept varies greatly. This leads to conceptual slippage as well as imprecise tests of the causes and consequences of affective polarisation.
Bert N. Bakker, Yphtach Lelkes
openaire +2 more sources
Does abscisic acid affect strigolactone biosynthesis? [PDF]
Strigolactones are considered a novel class of plant hormones that, in addition to their endogenous signalling function, are exuded into the rhizosphere acting as a signal to stimulate hyphal branching of arbuscular mycorrhizal (AM) fungi and germination
Adie+76 more
core +4 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
AffectON: Incorporating Affect Into Dialog Generation [PDF]
Due to its expressivity, natural language is paramount for explicit and implicit affective state communication among humans. The same linguistic inquiry (e.g., How are you?) might induce responses with different affects depending on the affective state of the conversational partner(s) and the context of the conversation. Yet, most dialog systems do not
arxiv
Symbolic Manipulators Affect Mathematical Mindsets
Symbolic calculators like Mathematica are becoming more commonplace among upper level physics students. The presence of such a powerful calculator can couple strongly to the type of mathematical reasoning students employ.
Arcavi A.+15 more
core +1 more source
Thematic relations affect similarity via commonalities [PDF]
Thematic relations are an important source of perceived similarity. For instance, the rowing theme of boats and oars increases their perceived similarity. The mechanism of this effect, however, has not been specified previously.
Estes, Zachary, Golonka, Sabrina
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source