Results 81 to 90 of about 4,441,387 (268)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Interventions for major depressive disorder: the role of automatic emotion regulation

Stress and Brain, 2023
Jiachen Qu, Salvatore Campanella, Jiajin Yuan   +2 more
doaj   +1 more source

Politics of Race, Belonging and Community in Yeboyah's music video ‘Elovena’

Journal of Extreme Anthropology
The Elovena maiden is, for some, one of the most important cultural symbols of the Finnish identity. This character has traditionally been portrayed as a blond, blue-eyed white woman and repeatedly used in artistic and commercial contexts.
Dragana Cvetanović , Inka Rantakallio, Elina Westinen, Kjetil Klette-Bøhler   +3 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Young investors, precariousness, and the maturing asset economy

Finance and Society
Enamoured by gamified FinTech platforms and the rise of investment cultures on social media, young people are turning to financial markets to take control over their future in a present shaped by instability and crisis.
Monique de Jong McKenzie
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Older men in motion: bodies, masculinities, and redefinition of identity

Frontiers in Psychology
IntroductionThis study explores the intersection of physical exercise, masculinity, and aging in older men, examining how these elements shape identity and bodily experiences. Aging is often framed through deficit-based narratives that emphasize decline;
Gustavo González-Calvo, Alfonso García-Monge, André Ramalho, André Ramalho, Faten Hamdi, Pedro Duarte-Mendes, Pedro Duarte-Mendes   +6 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Cross-cultural validation of the profile of mood scale: evaluation of the psychometric properties of short screening versions

Frontiers in Psychology
The Profile of Mood States (POMS) is one of the most widely applied scales for measuring mood. Considering the advantages of short scales and increased international research, the aim of the present study was to evaluate cross-culturally the psychometric
Ileana Schmalbach, Bjarne Schmalbach, Alireza Aghababa, Ralf Brand, Yu-Kai Chang, Muhammet Cihat Çiftçi, Hassan Elsangedy, Jesús Fernández Gavira, Zhijian Huang, Hafrún Kristjánsdóttir, Luca Mallia, Sanaz Nosrat, Caterina Pesce, Daði Rafnsson, Daniel Medina Rebollo, Sinika Timme, Elmar Brähler, Elmar Brähler, Katja Petrowski   +18 more
doaj   +1 more source