Results 41 to 50 of about 518,027 (311)

Culture as Non-Consensus: Exploring Coherence Among Native Speakers’ Perceptions of German Expressions of Affection [PDF]

open access: yes, 2020
From early in their learning experience, foreign language (FL) learners at American universities explore socio-cultural connotations that, it is argued, are signified by FL words.
Fichtner, Friederike
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Nonclassicality of noisy quantum states

open access: yes, 2005
Nonclassicality conditions for an oscillator-like system interacting with a hot thermal bath are considered. Nonclassical properties of quantum states can be conserved up to a certain temperature threshold only.
Lev, B. I.   +2 more
core   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Affective Paternalism

open access: yesBehavioural Public Policy, 2021
Many decisions are curated, incentivised, or nudged by a third party. Despite this, only a handful of studies have looked at paternalistic decision-makers and the processes by which they arrive at their decisions. The role of affect, in particular, has been ignored so far, and yet restricting agency on a potentially large group of people might be ...
Dolan, Paul   +2 more
openaire   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Psychometric Evaluation and Standardization of the Persian Adaptation of the APGAR Questionnaire Among Adults [PDF]

open access: yesPractice in Clinical Psychology
Objective: Family functioning profoundly influences individual psychological resilience and well-being. This research sought to examine the psychometric properties, including validity, reliability, and standardization of the Persian family adaptability ...
Nazanin Parhizgar   +3 more
doaj  

Relationship Quality among Married Couples [PDF]

open access: yes, 2016
Having a high quality relationship is a key part of a marriage. In this project, I performed an econometric analysis to determine what impacts a couple\u27s relationship quality.
Haack, Amber R
core   +2 more sources

Model of Empowerment to Improve Autonomy Directly Observed Treatment (DOT) Tuberculosis Patients [PDF]

open access: yes, 2016
Empowerment as not yet optimal health promotion efforts done to enhance the autonomy of Directly Observed Treatment (DOT), which affect the success of the recovery of patients with pulmonary tuberculosis.
Abdullah, E. (Endang)   +3 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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