Results 71 to 80 of about 202,687 (347)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Scottish Journal of Residential Child Care, 2018 I discuss the excessive toys and presents that were expected to make up for the lack of affection in my first foster home. I compare life at home to life in care using money and love as a theme.
Olivia Khan
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
A Multinational Comparison of Grandchildren’s Received Affection from Their Grandparents
Journal of Intergenerational Relationships, 2019 This study sought to address the need for systematic, quantitative cross-cultural comparisons to extend our knowledge of the interplay between cultural backgrounds and human behaviors.
D. Mansson, Aldís G. Sigurðardóttir
semanticscholar +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Affection of Law: Fichte on the Place and Boundaries of Pure Ethics of the Imperative
Кантовский сборник, 2019 In his popular 1806 lectures on religion Fichte considered five possible worldviews in the second of which, “the standpoint of legality”, one can readily recognise the ethics of law of the Stoical and Kantian type.
Sudakov A. K.
doaj +1 more source
The Technology of the Cute Body
Eidos. A Journal for Philosophy of Culture, 2018 This article considers the appeal of the cute body and its ambiguous relationship with the lovable. While cuteness is an aesthetic that is subjectively determined and expressed, it can also embellish a body with features that are standardized by systems ...
Joel Gn
doaj +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
La φιλοστοργία chez Fronton, une vertu sans équivalent latin ?
Aitia, 2011 Oscillating between two meanings - the love of a living being for its offspring, or among Christian authors, the deep affection - the philostorgia seems to have no exact equivalent in Latin : in their correspondence indeed, both Cicero and Fronto use ...
Sophie Aubert
doaj +1 more source