Results 141 to 150 of about 6,130,812 (344)

Affective games:a multimodal classification system [PDF]

open access: yes, 2018
Affective gaming is a relatively new field of research that exploits human emotions to influence gameplay for an enhanced player experience. Changes in player’s psychology reflect on their behaviour and physiology, hence recognition of such variation is ...
Hamdy, Salma, King, David
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Empathy for Pain Involves the Affective but not Sensory Components of Pain

open access: yesScience, 2004
T. Singer   +5 more
semanticscholar   +1 more source

Post-Theory and Beyond

open access: yesRevista Brasileira de Literatura Comparada
This article surveys and assesses the eclectic trends in literary theory and criticism in the posttheory age with a focus on three rubrics: the cultural turn, the historic turn, and the affective turn.
Luiz Fernando Valente
doaj  

Predicting Sensory and Affective Tactile Perception from Physical Parameters Obtained by Using a Biomimetic Multimodal Tactile Sensor

open access: yesSensors
Tactile perception plays a crucial role in the perception of products and consumer preferences. This perception process is structured in hierarchical layers comprising a sensory layer (soft and smooth) and an affective layer (comfort and luxury). In this
Toshiki Ikejima   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A POMDP approach to Affective Dialogue Modeling [PDF]

open access: yes, 2007
We propose a novel approach to developing a dialogue model that is able to take into account some aspects of the user's affective state and to act appropriately.
Bui, Trung H.   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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