Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
How serving helps leading: mediators between servant leadership and affective commitment. [PDF]
Front Psychol, 2023 Bai M +6 more
europepmc +1 more source
Pengaruh Affective Commitment Terhadap Service Quality Melalui Organizational Citizenship Behavior Sebagai Variabel Mediasi Di Depot 369 [PDF]
, 2016 Penelitian ini difokuskan pada Affective Commitment, Organizational Citizenship Behavior, Service Quality dimana penelitian ini digunakan untuk mengetahui pengaruh Organizational Citizenship Behavior terhadap Affective Commitment dan Service Quality di ...
Gunady, L. J. (Lelita) +3 more
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The associations between benevolent leadership, affective commitment, work engagement and helping behavior of nurses: a cross-sectional study. [PDF]
BMC Nurs, 2023 Shen X +6 more
europepmc +1 more source
Predicting turnover intention: Do organizational support and organizational commitment play a role? [PDF]
, 2013 This paper reports research investigating factors that might influence employees’ turnover intention.The study was a cross sectional study where respondents’ perception was measured at one point in time. 105 respondents participated in this study.
Mohd Shkuri, Nur Syafiqah +1 more
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Enhancing the work engagement of frontline nurses during the COVID-19 pandemic: the mediating role of affective commitment and perceived organizational support. [PDF]
BMC Nurs, 2023 Shan Y, Zhou X, Zhang Z, Chen W, Chen R.
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Unraveling the Puzzle of Turnover Intention: Exploring the Impact of Home-Work Interface and Working Conditions on Affective Commitment and Job Satisfaction. [PDF]
Behav Sci (Basel), 2023 Moslehpour M +4 more
europepmc +1 more source