Results 91 to 100 of about 952,740 (352)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Contemplating Mindfulness at Work: An Integrative Review [PDF]
, 2015 Mindfulness research activity is surging within organizational science. Emerging evidence across multiple fields suggests that mindfulness is fundamentally connected to many aspects of workplace functioning, but this knowledge base has not been ...
Baer, Ruth A. +8 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
How Does Job Well-Being Optimize Audit Performance? The Moderating Effect of Passion
Behavioral SciencesMost prior studies found that job well-being and job performance are in a linear relationship. Audit firms are a type of highly professional organization.
Kuo-Chih Cheng +6 more
doaj +1 more source
An Examination of the Demographic Antecedents and Job Outcomes of Participation in Employee Resource Groups (ERGs) [PDF]
, 2018 Employee resource groups (ERGs) are voluntary, employee-led groups formed in the workplace that focus on providing mutual support for members and that educate the organization about its members’ culture, identity, or experiences.
Lopez, Emily Erin
core +1 more source
A fuzzy-based approach for classifying students' emotional states in online collaborative work [PDF]
, 2016 (c) 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works for resale or ...
Arguedas, Marta +5 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Behavioral SciencesAlgorithmic technological progress presents both opportunities and challenges for organizational management. The success of online labor platforms hinges on algorithmic control, making it imperative to explore how this control affects gig workers ...
Xuedong Liang +3 more
doaj +1 more source
Beauty and the Beastly Prime Minister [PDF]
, 2014 This essay examines the so-called “turn to beauty” in British fiction since the 1990s as a response to the political and social consequences of Thatcherism. Focusing primarily on four texts—Jonathan Coe’s What a Carve Up! (1994), Julian Barnes’s England,
Su, John J.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source