Results 101 to 110 of about 886,679 (343)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Automated annotation of multimedia audio data with affective labels for information management [PDF]

, 2005
The emergence of digital multimedia systems is creating many new opportunities for rapid access to huge content archives. In order to fully exploit these information sources, the content must be annotated with significant features. An important aspect of
Hau Chan, Ching, Jones, Gareth J.F.
core  

How Does Job Well-Being Optimize Audit Performance? The Moderating Effect of Passion

Behavioral Sciences
Most prior studies found that job well-being and job performance are in a linear relationship. Audit firms are a type of highly professional organization.
Kuo-Chih Cheng, Yuan-Sheng Lin, Tung-Chin Yang, Tsung-Fu Chuang, Hsiu-Mei Lai, Lan-Hui Lin, Shao-Hsi Chung   +6 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Emotion meets action : towards an integration of research and theory [PDF]

, 2017
Action ...
Deonna, Julien, Hommel, Bernhard, Moors, Agnes, Sander, David   +3 more
core   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

POZİTİF VE NEGATİF DUYGUSALLIĞIN ÇALIŞANLARIN PERFORMANSLARI ÜZERİNDEKİ ETKİSİ

Sosyal Ekonomik Araştırmalar Dergisi, 2009
Bu çalışma Duygusal Olaylar Teorisi’ne dayanılarak bireylerin duygularının veya duygusallıklarının örgütsel yaşamdaki performansları üzerindeki etkisini belirlemeye yönelik olarak yapılmıştır.
Yasemin Doğan, Mahmut Özdevecioğlu
doaj   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Happy software developers solve problems better: psychological measurements in empirical software engineering [PDF]

, 2014
For more than 30 years, it has been claimed that a way to improve software developers' productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy.
Abrahamsson, Pekka, Graziotin, Daniel, Wang, Xiaofeng   +2 more
core   +2 more sources

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source