Results 81 to 90 of about 886,679 (343)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Subjective and Non-subjective Information in Children’s Allegations of Abuse [PDF]
, 2013 In this study, we were interested in how interviewers elicit subjective information in investigations of child abuse (e.g., descriptions of thoughts, emotions, opinions). Sixty-one interviews of children aged 4-12 years old were analyzed to determine the
Newman, Jennifer E., Roberts, Kim P.
core +2 more sources
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
The affective primacy hypothesis: Affective or cognitive processing of optimally and suboptimally presented primes? [PDF]
, 1996 Copyright 1996 Psychologica Belgica. Author version of the paper reproduced here with permission from the publisher.The aim of the present study was to pursue the research on the affective primacy hypothesis, which claims that positive and negative ...
Erauw, K +2 more
core
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Psychology Research and Behavior Management, 2020 Zeying Li,1,2 Bin He,2 Xu Sun2 1School of Computer Information Engineering, Hanshan Normal University, Chaozhou 521000, People’s Republic of China; 2School of Management, Guangdong University of Technology, Guangzhou 510520, People’s Republic
Li Z, He B, Sun X
doaj
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
An Examination of the Demographic Antecedents and Job Outcomes of Participation in Employee Resource Groups (ERGs) [PDF]
, 2018 Employee resource groups (ERGs) are voluntary, employee-led groups formed in the workplace that focus on providing mutual support for members and that educate the organization about its members’ culture, identity, or experiences.
Lopez, Emily Erin
core +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Learning Theories and Historical Events Affecting Instructional Design in Education [PDF]
Sage Open, 2012 How learning occurs has been a question pondered by the masses since formal education began thousands of years ago. Understanding the process has included many paradigm shifts in thought and practice. A thorough look at one major paradigm shift occurred in the past century, which has led to a plethora of ideas when identifying best practices to ...
openaire +3 more sources