Results 81 to 90 of about 1,372,797 (253)

Beyond diagnosis: symptom patterns across complex PTSD and borderline personality disorder

Frontiers in Psychiatry
BackgroundComplex post-traumatic stress disorder (cPTSD) and borderline personality disorder (BPD) share overlapping clinical features, complicating accurate diagnosis and treatment. This overlap has fueled ongoing discussions regarding whether cPTSD and
Joe J. Simon, Joe J. Simon, Kristin Spiegler, Kadiatou Coulibaly, Marion A. Stopyra, Marion A. Stopyra, Hans-Christoph Friederich, Hans-Christoph Friederich, Oliver Gruber, Christoph Nikendei   +9 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Affective and Cognitive Information Behavior: Interaction Effects in Internet Use [PDF]

, 2005
The presence and influence of affective variables in information behavior was studied. Affective load (AL), a compound variable consisting of uncertainty and technophobia measures, was found to be present in a variety of simple and complex information ...
Nahl, Diane
core   +1 more source

The relationship between cognitive and affective control and symptoms of depression and anxiety across the lifespan: A 3-wave longitudinal study

Comprehensive Psychiatry
Introduction: The association between cognitive functioning and mental health symptoms across the lifespan remains poorly understood. Understanding the directionality of the association between mental health and cognition is important as most gold ...
Anson Kai Chun Chau, Savannah Minihan, Sakiko Okayama, Susanne Schweizer   +3 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Physical Activity Decreases Somatic Symptom Distress in the Affect and Symptom Paradigm

Biopsychosocial Science and Medicine
Objective: According to recent empirical taxonomies (eg, the Hierarchical Taxonomy of Psychopathology), somatic symptom distress represents a transdiagnostically relevant dimension of psychopathology. To better understand the mechanisms, somatic symptoms can be experimentally provoked by inducing negative affect (in the Affect ...
Petzke, Tara M., Köteles, Ferenc, Van den Bergh, Omer, Witthöft, Michael   +3 more
openaire   +5 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Clinical Characteristics, Life Adversities and Personality Traits in Monozygotic Twins With, at Risk of and Without Affective Disorders

Frontiers in Psychiatry, 2018
Background: Affective disorders have a long-term impact on psychiatric health and are caused by multiple interacting factors including familial risk, childhood adversity, life events and personality traits.Methods: In this study, monozygotic twins (MZ ...
Ninja M. Ottesen, Iselin Meluken, Thomas Scheike, Thomas Scheike, Lars V. Kessing, Kamilla W. Miskowiak, Kamilla W. Miskowiak, Maj Vinberg   +7 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Maternal prenatal depressive symptoms and child brain responses to affective touch at two years of age

Publisher Copyright: © 2024 The AuthorsBackground: Touch is an essential form of mother-child interaction, instigating better social bonding and emotional stability.
Tuulari, Jetro J., Shekhar, Shashank, Maria, Ambika, Karlsson, Linnea, Kotilahti, Kalle, Hirvi, Pauliina, Karlsson, Hasse, Nissilä, Ilkka   +7 more
core   +1 more source