Results 81 to 90 of about 1,885,142 (291)

Beyond diagnosis: symptom patterns across complex PTSD and borderline personality disorder

open access: yesFrontiers in Psychiatry
BackgroundComplex post-traumatic stress disorder (cPTSD) and borderline personality disorder (BPD) share overlapping clinical features, complicating accurate diagnosis and treatment. This overlap has fueled ongoing discussions regarding whether cPTSD and
Joe J. Simon   +9 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

The relationship between cognitive and affective control and symptoms of depression and anxiety across the lifespan: A 3-wave longitudinal study

open access: yesComprehensive Psychiatry
Introduction: The association between cognitive functioning and mental health symptoms across the lifespan remains poorly understood. Understanding the directionality of the association between mental health and cognition is important as most gold ...
Anson Kai Chun Chau   +3 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Professional guide to signs and symptoms

open access: yes, 2007
ix.870hal.;14 ...
symptoms
core  

Clinical Characteristics, Life Adversities and Personality Traits in Monozygotic Twins With, at Risk of and Without Affective Disorders

open access: yesFrontiers in Psychiatry, 2018
Background: Affective disorders have a long-term impact on psychiatric health and are caused by multiple interacting factors including familial risk, childhood adversity, life events and personality traits.Methods: In this study, monozygotic twins (MZ ...
Ninja M. Ottesen   +7 more
doaj   +1 more source

Neuropsychiatric symptoms in cognitively normal older persons, and the association with Alzheimer’s and non-Alzheimer’s dementia

open access: yesAlzheimer’s Research & Therapy, 2020
Background Neuropsychiatric symptoms (NPS) have been reported to be useful in predicting incident dementia among cognitively normal older persons.
Tau Ming Liew
doaj   +1 more source

Physical Activity Decreases Somatic Symptom Distress in the Affect and Symptom Paradigm

open access: yesBiopsychosocial Science and Medicine
Objective: According to recent empirical taxonomies (eg, the Hierarchical Taxonomy of Psychopathology), somatic symptom distress represents a transdiagnostically relevant dimension of psychopathology. To better understand the mechanisms, somatic symptoms can be experimentally provoked by inducing negative affect (in the Affect ...
Petzke, Tara M.   +3 more
openaire   +5 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

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