Results 71 to 80 of about 1,885,142 (291)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Physical Work Environment in relation to the Physical and Psychological Symptoms of Sick Building Syndrome [PDF]

, 2011
This study investigated the relationship between perceptions of a poor physical work environment (PWE) and sick building syndrome (SBS), and with various psychological variables that impact organizational productivity.
Meikle, Sarah Marie
core  

Affective incoherence: when affective concepts and embodied reactions clash. [PDF]

, 2009
In five studies, the authors examined the effects on cognitive performance of coherence and incoherence between conceptual and experiential sources of affective information.
Centerbar, David B., Clore, Gerald L., Garvin, Erika D., Schnall, Simone   +3 more
core   +2 more sources

Affective temperament and mood spectrum symptoms in workers suffering from work-related stress disorders

, 2022
Adjustment Disorders (AD) which develop in response to work-related stressors represent a model of psychiatric occupational disease. Major Depressive Episodes (MDE) although often associated to work-related stressors are unlikely recognized by insurance ...
Foddis, Rudy, Chiumiento, Martina, Caldi, Fabrizio, Veltri, Antonello, Guglielmi, Giovanni, Carmassi, Claudia, Corsi, Martina, Baldanzi, Sigrid, Dell'Osso, Liliana, Buselli, Rodolfo, Marino, Riccardo, Cristaudo, Alfonso   +11 more
core   +1 more source

Antidepressant Drugs and Physical Activity: A Possible Synergism in the Treatment of Major Depression?

Frontiers in Psychology, 2020
Major depressive disorder (MDD) is a severe mental illness that affects 5–20% of the general population. Current antidepressant drugs exert only a partial clinical efficacy because approximately 30% of depressed patients failed to respond to these drugs ...
Claudia Savia Guerrera, Claudia Savia Guerrera, Giovanna Furneri, Giovanna Furneri, Margherita Grasso, Margherita Grasso, Giuseppe Caruso, Sabrina Castellano, Filippo Drago, Santo Di Nuovo, Filippo Caraci, Filippo Caraci   +11 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring [PDF]

, 2009
Background Adverse effects of maternal substance use during pregnancy on fetal development may increase risk of psychopathology. Aims To examine whether maternal use of tobacco, cannabis or alcohol during pregnancy increases risk of offspring ...
David Gunnell, Dieter Wolke, Jeremy Horwood, Kate Thomas, Andrew Thompson, Gunnell, David, Lewis, Glyn, Harrison, Glynn, Stanley Zammit, Paulo Menezes, Hollis, Chris, Glyn Lewis, Wolke, Dieter, Zammit, Stanley, Horwood, Jeremy, Thomas, Kate, Thompson, Andrew D., Menezes, Paulo, Chris Hollis, Glynn Harrison, Thompson, Andrew   +20 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

The Problem of Qualifying Affective Symptoms in the Differential Diagnosis of Mental Disorders

Теоретическая и экспериментальная психология
Background. Currently, there is a growing number of diagnosed mental disorders worldwide. The specialist conducting the diagnosis works under time constraints as determined by regulations per patient.
Leonora S. Pechnikova, Anna V. Petukhova, Ivan A. Gorbatenko   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source