Results 91 to 100 of about 3,708,183 (299)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Enjeux éthiques de la propagation de la rumeur sur Twitter : l’impouvoir d’action des publics affectifs

open access: yesInterfaces Numériques
Cette contribution est le résultat d’une recherche exploratoire qui vise à saisir les pouvoirs d’agir des usagers des réseaux socionumériques au cours de leur participation à la propagation d’une rumeur en ligne.
Nathanaëla ANDRIANASOLO, Fidelia IBEKWE
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Out of the day, time and life: Phenomenology and Cavescapes [PDF]

open access: yes, 2021
Affects of cavescapes: It is a paradox; perhaps our confidence in a scientific approach sometimes make us miss the point. Archaeologists cherish caves as a place for fortunate discoveries – they are containers of well- preserved things from the deep past;
Bjerck, Hein Bjartmann
core  

‘Currying Identities’: A Literary Re-Crafting of South-Asian Identities through Diasporic Women’s Cookbooks

open access: yesHumanities
Food has been an enduring presence in the construction of collective identities of migrant communities. From honing cooking techniques and selecting ingredients and tools to developing cultures of consumption and appreciation, diasporic communities seem ...
Dhrupadi Chattopadhyay   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Weather Spaces, Mobilities and Affects

open access: yes, 2020
This book delves into the everyday spaces, diverse mobilities and affective potency of weather. It presents cutting-edge research into the multiplicity of weather phenomena and analyses the lived experiences of humans in conjunction with contemporary ...
Edensor, Tim   +2 more
core   +1 more source

How location affects friendship interactions

open access: yes, 2015
Little is known about how social interactions are affected by geographical distance. This column argues that students tend to interact more with those who are highly central in the network of social contacts, and who are geographically closer ...
Patacchini, Eleonora   +2 more
core   +1 more source

Article 353 du code pénal de Tanguy Viel : la tension entre le langage juridique et affectif

open access: yesActa Universitatis Carolinae Philologica, 2018
Is a direct expression of feelings still possible in the novel of the 21st century? This article examines how Tanguy Viel, a contemporary author publishing in Les Editions de Minuit and considered as an experimental writer, deals with reader ’s emotions ...
Sylviane Coyault
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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