Results 31 to 40 of about 825,827 (307)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Characterizing socially avoidant and affiliative responses to social exclusion

open access: yesFrontiers in Integrative Neuroscience, 2012
Humans have a fundamental need for social relationships. From an evolutionary standpoint, the drive to form social connections may have evolved as an adaptive mechanism to promote survival, as group membership afforded the benefits of shared resources ...
Katherine Elizabeth Powers   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Cascade Faster R-CNN Detection for Vulnerable Plaques in OCT Images

open access: yesIEEE Access, 2021
Through the application of optical coherence tomography (OCT), computerized medical image analysis can provide intelligent, auxiliary diagnosis for patients with atherosclerosis.
Chao-Yu Sun   +5 more
doaj   +1 more source

Symposium Presenters [PDF]

open access: yes, 2017
Listing of symposium presenters and their institutional ...
Editorial Board
core   +1 more source

Personality and Affiliation in a Cooperative Task for Bottlenose Dolphin (Tursiops truncatus) Dyads [PDF]

open access: yes, 2020
Social species can depend on each other for survival, helping in rearing of young, predator defense, and foraging. Personality dynamics between individuals may influence cooperative behaviors.
Bagley, Kimberly Corinne   +3 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

More than a face: A unified theoretical perspective on nonverbal social cue processing in social anxiety

open access: yesFrontiers in Human Neuroscience, 2013
Processing of nonverbal social cues (NVSCs) is essential to interpersonal functioning and is particularly relevant to models of social anxiety. This article provides a review of the literature on NVSC processing from the perspective of social rank and ...
Eva eGilboa-Schechtman   +1 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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